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bub3 BUB3 mitotic checkpoint protein [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493224, updated on 4-Nov-2024

Summary

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Official Symbol
bub3provided by Xenbase
Official Full Name
BUB3 mitotic checkpoint proteinprovided by Xenbase
Primary source
Xenbase:XB-GENE-955683
See related
Ensembl:ENSXETG00000009564 AllianceGenome:Xenbase:XB-GENE-955683
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
xbub3
Summary
Predicted to act upstream of or within meiotic cell cycle. Predicted to be located in nucleus. Orthologous to human BUB3 (BUB3 mitotic checkpoint protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See bub3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (20075210..20089339, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (11746519..11785967, complement)

Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene carboxypeptidase X (M14 family), member 2 Neighboring gene G protein-coupled receptor 26 Neighboring gene H6 family homeobox 2 Neighboring gene H6 family homeobox 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC79574

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitotic checkpoint protein BUB3
Names
budding uninhibited by benzimidazoles 3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007497.2 → NP_001007498.2  mitotic checkpoint protein BUB3

    Status: VALIDATED

    Source sequence(s)
    CR760647
    UniProtKB/TrEMBL
    F6VP72, F6WBJ4, Q28I10
    Related
    ENSXETP00000111085.1, ENSXETT00000122754.1
    Conserved Domains (2) summary
    sd00039
    Location:23 → 60
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:20 → 302
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    20075210..20089339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031905009.1 → XP_031760869.1  mitotic checkpoint protein BUB3 isoform X1

    UniProtKB/TrEMBL
    F6VP72, F6WBJ4, Q28I10
    Related
    ENSXETP00000080695.1, ENSXETT00000069469.2
    Conserved Domains (2) summary
    sd00039
    Location:23 → 60
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:20 → 302
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_031905011.1 → XP_031760871.1  mitotic checkpoint protein BUB3 isoform X2

    UniProtKB/TrEMBL
    F6VP72, Q68FA8
    Related
    ENSXETP00000021098.3, ENSXETT00000021098.4
    Conserved Domains (2) summary
    sd00039
    Location:17 → 54
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:14 → 296
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_031905010.1 → XP_031760870.1  mitotic checkpoint protein BUB3 isoform X1

    UniProtKB/TrEMBL
    F6VP72, F6WBJ4, Q28I10
    Related
    ENSXETP00000105224.1, ENSXETT00000114057.1
    Conserved Domains (2) summary
    sd00039
    Location:23 → 60
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:20 → 302
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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