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LGI2 leucine rich repeat LGI family member 2 [ Canis lupus familiaris (dog) ]

Gene ID: 488853, updated on 5-Mar-2024

Summary

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Official Symbol
LGI2provided by VGNC
Official Full Name
leucine rich repeat LGI family member 2provided by VGNC
Primary source
VGNC:VGNC:49726
See related
Ensembl:ENSCAFG00845007610
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See LGI2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (86155381..86187875)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (87694029..87726513)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (85779270..85811791)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (85288432..85320930)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (85393580..85426122)

Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase type 2 beta Neighboring gene Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase Neighboring gene uncharacterized LOC102154940 Neighboring gene uncharacterized LOC119870877 Neighboring gene coiled-coil domain containing 149 Neighboring gene uncharacterized LOC111095318

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LGI2 truncation causes a remitting focal epilepsy in dogs. Seppälä EH, et al. PLoS Genet, 2011 Jul. PMID 21829378, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inhibitory synapse assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat LGI family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051807.1 Reference ROS_Cfam_1.0

    Range
    86155381..86187875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662064.1 → XP_038517992.1  leucine-rich repeat LGI family member 2

    UniProtKB/TrEMBL
    A0A8C0RAS5, A0A8P0NHY5
    Related
    ENSCAFP00845010408.1, ENSCAFT00845013415.1
    Conserved Domains (4) summary
    TIGR00864
    Location:141 → 216
    PCC; polycystin cation channel protein
    sd00031
    Location:112 → 135
    LRR_1; leucine-rich repeat [structural motif]
    pfam03736
    Location:267 → 305
    EPTP; EPTP domain
    pfam13855
    Location:111 → 170
    LRR_8; Leucine rich repeat

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049263.1 Alternate UMICH_Zoey_3.1

    Range
    85288432..85320930
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038472574.1 → XP_038328502.1  leucine-rich repeat LGI family member 2

    Conserved Domains (4) summary
    TIGR00864
    Location:141 → 216
    PCC; polycystin cation channel protein
    sd00031
    Location:112 → 135
    LRR_1; leucine-rich repeat [structural motif]
    pfam03736
    Location:267 → 305
    EPTP; EPTP domain
    pfam13855
    Location:111 → 170
    LRR_8; Leucine rich repeat

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

    Range
    85393580..85426122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038597842.1 → XP_038453770.1  leucine-rich repeat LGI family member 2

    Conserved Domains (4) summary
    TIGR00864
    Location:141 → 216
    PCC; polycystin cation channel protein
    sd00031
    Location:112 → 135
    LRR_1; leucine-rich repeat [structural motif]
    pfam03736
    Location:267 → 305
    EPTP; EPTP domain
    pfam13855
    Location:111 → 170
    LRR_8; Leucine rich repeat

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

    Range
    85779270..85811791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038533560.1 → XP_038389488.1  leucine-rich repeat LGI family member 2

    UniProtKB/TrEMBL
    A0A8C0LVH3, A0A8C0RAS5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    87694029..87726513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022416405.2 → XP_022272113.2  leucine-rich repeat LGI family member 2

    UniProtKB/TrEMBL
    A0A8C0RAS5, A0A8P0NHY5
    Conserved Domains (4) summary
    TIGR00864
    Location:141 → 216
    PCC; polycystin cation channel protein
    sd00031
    Location:112 → 135
    LRR_1; leucine-rich repeat [structural motif]
    pfam03736
    Location:267 → 305
    EPTP; EPTP domain
    pfam13855
    Location:111 → 170
    LRR_8; Leucine rich repeat
Nucleotide Protein
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