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XYL2 D-xylulose reductase (Xylitol dehydrogenase) (XDH) [ Scheffersomyces stipitis CBS 6054 ]

Gene ID: 4852013, updated on 19-Jun-2024

Summary

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Gene symbol
XYL2
Gene description
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
Locus tag
PICST_86924
Gene type
protein coding
RNA name
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
RefSeq status
PROVISIONAL
Organism
Scheffersomyces stipitis CBS 6054 (strain: CBS 6054)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces
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Genomic context

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See XYL2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_009068.1 (3415943..3417177)

Chromosome 1 - NC_009068.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ATP synthase delta subunit Neighboring gene mitochondrial 54S ribosomal protein YmL25 Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009068.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Thermostabilization of Pichia stipitis xylitol dehydrogenase by mutation of structural zinc-binding loop. Annaluru N, et al. J Biotechnol, 2007 May 10. PMID 17350704
  2. Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains. Tomás-Pejó E, et al. Biotechnol Bioeng, 2008 Aug 15. PMID 18383076
  3. Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Jeffries TW, et al. Nat Biotechnol, 2007 Mar. PMID 17334359
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Introduced in S.cerevisiae F12, succesfully enable it to metabolize xylose from cereal straw
    Title: Comparison of SHF and SSF processes from steam-exploded wheat straw for ethanol production by xylose-fermenting and robust glucose-fermenting Saccharomyces cerevisiae strains.
  2. A high thermostability of this enzyme was obtained by subsequent site-directed mutagenesis of the structural zinc-binding loop.
    Title: Thermostabilization of Pichia stipitis xylitol dehydrogenase by mutation of structural zinc-binding loop.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-iditol 2-dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sorbitol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
D-xylulose reductase (Xylitol dehydrogenase) (XDH)
XP_001386982.1
  • Xylitol dehydrogenase (XDH) similar to SOR1 deletion blocks xylitol utilization

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009068.1 Reference assembly

    Range
    3415943..3417177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001386945.1 → XP_001386982.1  D-xylulose reductase (Xylitol dehydrogenase) (XDH) [Scheffersomyces stipitis CBS 6054]

    See identical proteins and their annotated locations for XP_001386982.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A3GIB4, P22144, Q549G5
    UniProtKB/TrEMBL
    E5G6H4
    Conserved Domains (1) summary
    cd05285
    Location:6 → 361
    sorbitol_DH; Sorbitol dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22144.1

Gene LinkOut

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Research Materials