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FERMT3 FERM domain containing kindlin 3 [ Canis lupus familiaris (dog) ]

Gene ID: 483766, updated on 17-Aug-2024

Summary

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Official Symbol
FERMT3provided by VGNC
Official Full Name
FERM domain containing kindlin 3provided by VGNC
Primary source
VGNC:VGNC:40824
See related
Ensembl:ENSCAFG00845030758
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (53879047..53896895, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (51440706..51458507, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (53341355..53359153, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (52981873..52999678, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (52557448..52575268, complement)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene vascular endothelial growth factor B Neighboring gene DnaJ heat shock protein family (Hsp40) member C4 Neighboring gene nudix hydrolase 22 Neighboring gene tRNA phosphotransferase 1 Neighboring gene stress induced phosphoprotein 1 Neighboring gene mono-ADP ribosylhydrolase 1 Neighboring gene fibronectin leucine rich transmembrane protein 1 Neighboring gene uncharacterized LOC119864274

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell-cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-substrate junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fermitin family homolog 3
Names
fermitin family member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    53879047..53896895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425194.1 → XP_038281122.1  fermitin family homolog 3

    UniProtKB/TrEMBL
    A0A8C0R0Z1, A0A8C0SNN0, A0A8I3SCT4
    Related
    ENSCAFP00845042947.1, ENSCAFT00845054623.1
    Conserved Domains (6) summary
    smart00295
    Location:221 → 323
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:462 → 553
    FERM_M; FERM central domain
    cl28922
    Location:15 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    52981873..52999678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501457.1 → XP_038357385.1  fermitin family homolog 3

    Conserved Domains (6) summary
    smart00295
    Location:221 → 323
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:462 → 553
    FERM_M; FERM central domain
    cl28922
    Location:15 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    52557448..52575268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038628285.1 → XP_038484213.1  fermitin family homolog 3

    Conserved Domains (6) summary
    smart00295
    Location:221 → 323
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:462 → 553
    FERM_M; FERM central domain
    cl28922
    Location:15 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    53341355..53359153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038564140.1 → XP_038420068.1  fermitin family homolog 3

    UniProtKB/TrEMBL
    A0A8C0R0Z1, A0A8C0SNN0, A0A8I3SCT4
    Conserved Domains (6) summary
    smart00295
    Location:221 → 323
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:462 → 553
    FERM_M; FERM central domain
    cl28922
    Location:15 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51440706..51458507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003639655.4 → XP_003639703.2  fermitin family homolog 3

    UniProtKB/TrEMBL
    A0A8P0SJG2
    Conserved Domains (6) summary
    smart00295
    Location:221 → 323
    B41; Band 4.1 homologues
    cd01237
    Location:350 → 474
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:548 → 639
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17185
    Location:98 → 254
    FERM_F1_KIND3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-3 (KIND3)
    pfam00373
    Location:462 → 553
    FERM_M; FERM central domain
    cl28922
    Location:15 → 97
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein
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