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ERVK-7 endogenous retrovirus group K member 7 [ Homo sapiens (human) ]

Gene ID: 449619, updated on 14-Nov-2024

Summary

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Official Symbol
ERVK-7provided by HGNC
Official Full Name
endogenous retrovirus group K member 7provided by HGNC
Primary source
HGNC:HGNC:31828
See related
MIM:614013; AllianceGenome:HGNC:31828
Gene type
other
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ERVK7; HERV-K102; HERV-KIII; HERV-K(III)
Summary
Predicted to enable RNA stem-loop binding activity. Predicted to be involved in DNA metabolic process; proteolysis; and viral translational frameshifting. Predicted to be located in nucleus and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
1q22

Bibliography

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Related articles in PubMed

  1. The replicative activity of human endogenous retrovirus K102 (HERV-K102) with HIV viremia. Laderoute MP, et al. AIDS, 2007 Nov 30. PMID 18025878
  2. Neither an intronic CA repeat within the CD48 gene nor the HERV-K18 polymorphisms are associated with type 1 diabetes. Ramos-Lopez E, et al. Tissue Antigens, 2006 Aug. PMID 16866884
  3. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. Barbulescu M, et al. Curr Biol, 1999 Aug 26. PMID 10469592
  4. Quantitation of HERV-K env gene expression and splicing in human breast cancer. Wang-Johanning F, et al. Oncogene, 2003 Mar 13. PMID 12629516
  5. Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping. Sugimoto J, et al. Genomics, 2001 Mar 1. PMID 11401426

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Replication-competent, particle producing, HERV-K HML-2 Type I retrovirus with foamy-virus-like properties;innate host defence mechanism to bloodborne pathogens with temporary T and B cell responses to Env
    Title: The replicative activity of human endogenous retrovirus K102 (HERV-K102) with HIV viremia.
  2. Observational study of gene-disease association. (HuGE Navigator)
    Title: Neither an intronic CA repeat within the CD48 gene nor the HERV-K18 polymorphisms are associated with type 1 diabetes.
Submit: New GeneRIF Correction

General gene information

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Other Names

  • Endogenous retrovirus group K member 7 Gag polyprotein
  • Endogenous retrovirus group K member 7 Np9 protein
  • Endogenous retrovirus group K member 7 Pol protein
  • Endogenous retrovirus group K member 7 Pro protein
  • HERV-K(III) Gag protein
  • HERV-K(III) Np9 protein
  • HERV-K(III) Pol protein
  • HERV-K(III) Pro protein
  • HERV-K102 Gag protein
  • HERV-K102 Np9 protein
  • HERV-K102 Pol protein
  • HERV-K102 Pro protein
  • HERV-K_1q22 provirus Np9 protein
  • HERV-K_1q22 provirus ancestral Env polyprotein
  • HERV-K_1q22 provirus ancestral Gag polyprotein
  • HERV-K_1q22 provirus ancestral Pol protein
  • HERV-K_1q22 provirus ancestral Pro protein
  • endogenous retroviral sequence K, 7 (type 2)

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA stem-loop binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA-DNA hybrid ribonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
enables telomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA integration IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA synthesis involved in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA-templated DNA biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in viral process IEA
Inferred from Electronic Annotation
more info
  
involved_in viral translational frameshifting IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P61567.1 GenPept UniProtKB/Swiss-Prot:P61567
P61582.1 GenPept UniProtKB/Swiss-Prot:P61582
P63130.2 GenPept UniProtKB/Swiss-Prot:P63130
P63131.1 GenPept UniProtKB/Swiss-Prot:P63131
P63135.1 GenPept UniProtKB/Swiss-Prot:P63135

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