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nfkbia NFKB inhibitor alpha [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 448138, updated on 4-Nov-2024

Summary

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Official Symbol
nfkbiaprovided by Xenbase
Official Full Name
NFKB inhibitor alphaprovided by Xenbase
Primary source
Xenbase:XB-GENE-491079
See related
Ensembl:ENSXETG00000017950 AllianceGenome:Xenbase:XB-GENE-491079
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
ikba; mad-3; nfkbi
Summary
Human ortholog(s) of this gene implicated in several diseases, including childhood-onset asthma; ectodermal dysplasia and immunodeficiency 2; hematologic cancer (multiple); hepatitis B; and lung disease (multiple). Orthologous to human NFKBIA (NFKB inhibitor alpha). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See nfkbia in Genome Data Viewer
Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (109510957..109514694, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (89238397..89242137, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene protein only RNase P catalytic subunit Neighboring gene proteasome subunit alpha 6 Neighboring gene major histocompatibility complex, class 1, UC alpha chain Neighboring gene serine/arginine-rich splicing factor 5 alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC69359

General protein information

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Preferred Names
NF-kappa-B inhibitor alpha
Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004851.1 → NP_001004851.1  NF-kappa-B inhibitor alpha

    See identical proteins and their annotated locations for NP_001004851.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074672
    UniProtKB/TrEMBL
    F6YJM7, Q6GL40
    Related
    ENSXETP00000038920.4, ENSXETT00000038920.5
    Conserved Domains (3) summary
    PHA02741
    Location:176 → 281
    PHA02741; hypothetical protein; Provisional
    sd00045
    Location:147 → 182
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:118 → 214
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    109510957..109514694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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