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fnbp1l formin binding protein 1-like [ Danio rerio (zebrafish) ]

Gene ID: 445240, updated on 2-Nov-2024

Summary

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Official Symbol
fnbp1lprovided by ZNC
Official Full Name
formin binding protein 1-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-155
See related
Ensembl:ENSDARG00000020131 AllianceGenome:ZFIN:ZDB-GENE-040801-155
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100923
Summary
Predicted to enable lipid binding activity. Predicted to act upstream of or within autophagy; endocytosis; and signal transduction. Predicted to be located in several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Is expressed in several structures, including central nervous system; midbrain neural keel; neural plate; pronephric duct; and ventral mesoderm. Orthologous to human FNBP1L (formin binding protein 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See fnbp1l in Genome Data Viewer
Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (14987006..15081627)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (14949282..15043925)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene sterol O-acyltransferase 1 Neighboring gene c-abl oncogene 2, non-receptor tyrosine kinase Neighboring gene BCAR3 adaptor protein, NSP family member Neighboring gene polyamine oxidase (exo-N4-amino) 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos. Rauwerda H, et al. BMC Genomics, 2017 Apr 11. PMID 28399811, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
formin-binding protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003634.1 → NP_001003634.1  formin-binding protein 1-like

    See identical proteins and their annotated locations for NP_001003634.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077109
    UniProtKB/TrEMBL
    Q6DEK3
    Related
    ENSDARP00000045037.7, ENSDART00000045038.9
    Conserved Domains (3) summary
    cd11628
    Location:340 → 419
    HR1_CIP4_FNBP1L; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like
    cl12013
    Location:5 → 255
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl17036
    Location:480 → 536
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    14987006..15081627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478241.2 → XP_021333916.1  formin-binding protein 1-like isoform X2

    UniProtKB/TrEMBL
    A0A8M9QDQ3
    Conserved Domains (3) summary
    cd11628
    Location:391 → 470
    HR1_CIP4_FNBP1L; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like
    cd12072
    Location:531 → 587
    SH3_FNBP1L; Src Homology 3 domain of Formin Binding Protein 1-Like
    cl12013
    Location:5 → 255
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_068222930.1 → XP_068079031.1  formin-binding protein 1-like isoform X3

    Related
    ENSDARP00000144752.1, ENSDART00000191374.1

  3. XM_005166828.5 → XP_005166885.1  formin-binding protein 1-like isoform X1

    UniProtKB/TrEMBL
    A0A0R4IAX0, A0A8M2BEA0
    Related
    ENSDARP00000131086.2, ENSDART00000171867.2
    Conserved Domains (3) summary
    cd07675
    Location:5 → 255
    F-BAR_FNBP1L; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Formin Binding Protein 1-Like
    cd11628
    Location:391 → 470
    HR1_CIP4_FNBP1L; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like
    cd12072
    Location:531 → 587
    SH3_FNBP1L; Src Homology 3 domain of Formin Binding Protein 1-Like
Nucleotide Protein Strain
Heading Accession and Version

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