hmox2.S heme oxygenase 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: hmox2.S
Official Full Name: heme oxygenase 2 S homeolog
Primary source: Xenbase:XB-GENE-6255973
Locus tag: XELAEV_18002191mg
See related: AllianceGenome:Xenbase:XB-GENE-6255973
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ho-2; hmox2; hmox2.L
Summary: Predicted to enable heme binding activity; heme oxygenase (decyclizing) activity; and metal ion binding activity. Predicted to act upstream of or within heme catabolic process; heme oxidation; and response to oxidative stress. Is expressed in ectoderm. Orthologous to human HMOX2 (heme oxygenase 2). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (117086967..117100189, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694820.1 (155704..169038)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables heme oxygenase (decyclizing) activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within heme catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within heme oxidation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to oxidative stress	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heme oxygenase 2 S homeolog

Names: heme oxygenase (decycling) 2; heme oxygenase 2 L homeolog

NP_001085675.1

EC 1.4.9.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092206.1 → NP_001085675.1 heme oxygenase 2 S homeolog

See identical proteins and their annotated locations for NP_001085675.1

Status: PROVISIONAL

Source sequence(s)

BC073183

UniProtKB/TrEMBL

Q6GPF6

Conserved Domains (2) summary

cd19165
Location:139 → 166

HemeO; kinked helix [structural motif]

pfam01126
Location:24 → 228

Heme_oxygenase; Heme oxygenase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

117086967..117100189 complement

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GenBank, FASTA, Sequence Viewer (Graphics)