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cdc27.S cell division cycle 27 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 443994, updated on 4-Nov-2024

Summary

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Official Symbol
cdc27.S
Official Full Name
cell division cycle 27 S homeolog
Primary source
Xenbase:XB-GENE-972664
Locus tag
XELAEV_18046079mg
See related
EnsemblRapid:ENSXLAG00005035846 AllianceGenome:Xenbase:XB-GENE-972664
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cdc27
Summary
Predicted to act upstream of or within several processes, including anaphase-promoting complex-dependent catabolic process; metaphase/anaphase transition of mitotic cell cycle; and protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be part of anaphase-promoting complex. Orthologous to human CDC27 (cell division cycle 27). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cdc27.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (5627577..5661716)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (5490376..5524845)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene hexamethylene bis-acetamide inducible 1 S homeolog Neighboring gene phospholipase C delta 3 S homeolog Neighboring gene glycylpeptide N-tetradecanoyltransferase 1 Neighboring gene KAT8 regulatory NSL complex subunit 1 Neighboring gene microtubule associated protein tau S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Non-proteolytic ubiquitylation counteracts the APC/C-inhibitory function of XErp1. Hörmanseder E, et al. EMBO Rep, 2011 May. PMID 21399619, Free PMC Article
  2. The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions. Tischer T, et al. Science, 2012 Oct 26. PMID 23019610
  3. Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism. Tang W, et al. Mol Biol Cell, 2010 Aug 1. PMID 20534816, Free PMC Article
  4. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Zeng X, et al. Cancer Cell, 2010 Oct 19. PMID 20951947, Free PMC Article
  5. A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Wu Q, et al. Curr Biol, 2007 Feb 6. PMID 17276914, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC80529

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within anaphase-promoting complex-dependent catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within metaphase/anaphase transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cell division cycle 27 S homeolog; cell division cycle protein 27 homolog
Names
cell division cycle 27 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    5627577..5661716
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237450.2 → XP_018092939.1  cell division cycle protein 27 homolog

    UniProtKB/TrEMBL
    A0A1L8EL99, A0A974BS76, Q6GQ04
    Related
    ENSXLAP00005107663.1, ENSXLAT00005109801.1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001092099.1: Suppressed sequence

    Description
    NM_001092099.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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