cd44.L CD44 molecule (IN blood group) L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cd44.L
Official Full Name: CD44 molecule (IN blood group) L homeolog
Primary source: Xenbase:XB-GENE-6251905
Locus tag: XELAEV_18021845mg
See related: EnsemblRapid:ENSXLAG00005022566 AllianceGenome:Xenbase:XB-GENE-6251905
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: lhr; cd44; mc56; mdu2; mdu3; mic4; pgp1; XCD44; cdw44; cspg8; hcell; mutch-i; ecmr-iii
Summary: Predicted to enable cytokine receptor activity and hyaluronic acid binding activity. Acts upstream of or within mesenchymal stem cell proliferation. Predicted to be located in basolateral plasma membrane; extracellular region; and microvillus. Predicted to be part of macrophage migration inhibitory factor receptor complex. Is expressed in ectoderm; musculoskeletal system; nervous system; pharyngeal arch; and vestibuloauditory system. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)). [provided by Alliance of Genome Resources, Nov 2024]
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Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (7932423..7965532, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (8007340..8040726, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cytokine receptor activity	IEA Inferred from Electronic Annotation more info
enables hyaluronic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within inflammatory response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mesenchymal stem cell proliferation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
part_of macrophage migration inhibitory factor receptor complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in microvillus	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

Names: CD44 molecule (Indian blood group) L homeolog; hyaluronan receptor CD44

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The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_001091833.1: Suppressed sequence

Description

NM_001091833.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.