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GGCX gamma-glutamyl carboxylase [ Ovis aries (sheep) ]

Gene ID: 443129, updated on 10-Oct-2024

Summary

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Gene symbol
GGCX
Gene description
gamma-glutamyl carboxylase
See related
EnsemblRapid:ENSOARG00020002878
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See GGCX in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (57389119..57403887, complement)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132659394 Neighboring gene methionine adenosyltransferase 2A Neighboring gene uncharacterized LOC121819037 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene vesicle associated membrane protein 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hereditary deficiency of vitamin-K-dependent coagulation factors in Rambouillet sheep. Baker DC, et al. Blood Coagul Fibrinolysis, 1999 Mar. PMID 10192655
  2. A genome resource to address mechanisms of developmental programming: determination of the fetal sheep heart transcriptome. Cox LA, et al. J Physiol, 2012 Jun 15. PMID 22508961, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables gamma-glutamyl carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vitamin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-glutamic acid carboxylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vitamin K-dependent gamma-carboxylase
Names
peptidyl-glutamate 4-carboxylase
vitamin K gamma glutamyl carboxylase
NP_001009750.1
XP_060267579.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009750.1 → NP_001009750.1  vitamin K-dependent gamma-carboxylase

    See identical proteins and their annotated locations for NP_001009750.1

    Status: PROVISIONAL

    Source sequence(s)
    AF312035
    UniProtKB/Swiss-Prot
    Q9GL59
    UniProtKB/TrEMBL
    A0A836A6V5
    Related
    ENSOARP00020003649.2, ENSOART00020004442.2
    Conserved Domains (2) summary
    smart00752
    Location:56 → 315
    HTTM; Horizontally Transferred TransMembrane Domain
    pfam05090
    Location:66 → 502
    VKG_Carbox; Vitamin K-dependent gamma-carboxylase

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    57389119..57403887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060411596.1 → XP_060267579.1  vitamin K-dependent gamma-carboxylase isoform X1

    Related
    ENSOARP00020003673.2, ENSOART00020004469.2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GL59.1 GenPept UniProtKB/Swiss-Prot:Q9GL59

Gene LinkOut

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