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CG31075 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43244, updated on 18-Sep-2024

Summary

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Official Symbol
CG31075provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051075
Locus tag
Dmel_CG31075
See related
AllianceGenome:FB:FBgn0051075
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
150697_at; CG6309; CT19744; Dmel\CG31075; GH20910p
Summary
Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in pyruvate metabolic process. Predicted to be located in mitochondrion. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in isolated microphthalmia 8. Orthologous to several human genes including ALDH1A1 (aldehyde dehydrogenase 1 family member A1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG31075 in Genome Data Viewer
Location:
97D12-97D12; 3-92 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26985624..26988517, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22811346..22814239, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 97a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene TweedleC

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sex-dependent and sex-independent regulatory systems of size variation in natural populations. Okada H, et al. Mol Syst Biol, 2019 Nov. PMID 31777173, Free PMC Article
  2. The MicroRNA miR-277 Controls Physiology and Pathology of the Adult Drosophila Midgut by Regulating the Expression of Fatty Acid β-Oxidation-Related Genes in Intestinal Stem Cells. Zipper L, et al. Metabolites, 2022 Mar 31. PMID 35448502, Free PMC Article
  3. Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. Shim MS, et al. J Biol Chem, 2009 Nov 20. PMID 19755423, Free PMC Article
  4. Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. O'Keefe LV, et al. Hum Mol Genet, 2011 Feb 1. PMID 21075834, Free PMC Article
  5. Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila. Gallach M, et al. Genome Biol Evol, 2010. PMID 21037198, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aldehyde dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aldehyde dehydrogenase (NAD+) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in pyruvate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31075-PA
CG31075-PB
NP_001247324.1
NP_733183.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    26985624..26988517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170304.2 → NP_733183.1  uncharacterized protein Dmel_CG31075, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733183.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9UNE9, Q9VB96
    Related
    FBpp0084452
    Conserved Domains (1) summary
    cl11961
    Location:5 → 483
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

  2. NM_001260395.2 → NP_001247324.1  uncharacterized protein Dmel_CG31075, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247324.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6I6, A9UNE9
    Conserved Domains (1) summary
    cl11961
    Location:33 → 506
    ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K6I6 A0A0B4K6I6
Q9VB96 Q9VB96

Gene LinkOut

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