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ELOVL5 ELOVL fatty acid elongase 5 [ Gallus gallus (chicken) ]

Gene ID: 428646, updated on 10-Oct-2024

Summary

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Symbol
ELOVL5provided by CGNC
Full Name
ELOVL fatty acid elongase 5provided by CGNC
Primary source
CGNC:12203
See related
Ensembl:ENSGALG00010002135
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ELOVL5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (87928839..87966482)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (87734509..87772130)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110161 Neighboring gene glutamate-cysteine ligase catalytic subunit Neighboring gene uncharacterized LOC107053136 Neighboring gene glial cells missing homolog 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Estrogen Promotes Hepatic Synthesis of Long-Chain Polyunsaturated Fatty Acids by Regulating ELOVL5 at Post-Transcriptional Level in Laying Hens. Zhang M, et al. Int J Mol Sci, 2017 Jun 30. PMID 28665359, Free PMC Article
  2. Functional characterization of the chicken fatty acid elongases. Gregory MK, et al. J Nutr, 2013 Jan. PMID 23173174
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ELOVL5 expression rapidly increased in liver tissue during peak-laying stages
    Title: Estrogen Promotes Hepatic Synthesis of Long-Chain Polyunsaturated Fatty Acids by Regulating ELOVL5 at Post-Transcriptional Level in Laying Hens.
  2. investigation of ability of ELOVL5 and ELOVL2 to elongate docosapentaenoic acid and relative abundance of ELOVL5 and ELOVL2 in chicken liver; expression of these liver enzymes did not change with additional alpha-linolenic acid in feed
    Title: Functional characterization of the chicken fatty acid elongases.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fatty acid elongase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid elongation, monounsaturated fatty acid IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid elongation, polyunsaturated fatty acid IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid elongation, saturated fatty acid IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in very long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
very long chain fatty acid elongase 5; elongation of very long chain fatty acids protein 5
Names
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
elongation of long chain fatty acids family member 5
NP_001186126.1
XP_015140326.1
XP_040553241.1
XP_046770313.1
XP_046770314.1
XP_046770315.1
XP_046770316.1
XP_046794958.1
XP_046794959.1
XP_046794960.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199197.2 → NP_001186126.1  very long chain fatty acid elongase 5

    See identical proteins and their annotated locations for NP_001186126.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000065
    UniProtKB/TrEMBL
    A0A8V0XE38, E3VVZ8, F1NQZ8
    Related
    ENSGALP00010002867.1, ENSGALT00010004776.1
    Conserved Domains (1) summary
    pfam01151
    Location:28 → 261
    ELO; GNS1/SUR4 family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    87928839..87966482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015284840.4 → XP_015140326.1  elongation of very long chain fatty acids protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X898, A0A8V0XE33
    Related
    ENSGALP00010002859.1, ENSGALT00010004768.1
    Conserved Domains (1) summary
    pfam01151
    Location:73 → 306
    ELO; GNS1/SUR4 family

  2. XM_046939003.1 → XP_046794959.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8

  3. XM_046939002.1 → XP_046794958.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8

  4. XM_040697307.1 → XP_040553241.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XE38, E3VVZ8, F1NQZ8
    Conserved Domains (1) summary
    pfam01151
    Location:28 → 261
    ELO; GNS1/SUR4 family

  5. XM_046939004.1 → XP_046794960.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    87734509..87772130
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046914357.1 → XP_046770313.1  elongation of very long chain fatty acids protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X898

  2. XM_046914360.1 → XP_046770316.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8

  3. XM_046914359.1 → XP_046770315.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8

  4. XM_046914358.1 → XP_046770314.1  elongation of very long chain fatty acids protein 5 isoform X2

    UniProtKB/TrEMBL
    E3VVZ8, F1NQZ8
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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