TRIM71 tripartite motif containing 71 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: TRIM71provided by CGNC
Official Full Name: tripartite motif containing 71provided by CGNC
Primary source: CGNC:13926
See related: Ensembl:ENSGALG00010017609
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: LIN41; LIN-41
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (40434809..40490698, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (40484760..40540577, complement)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Lin-41 is genetically and biochemically downstream of both the Shh and Fgf signaling pathways and is expressed in three phases over developmental time and most notably is associated with the developing autopod.
Title: Analysis of the regulation of lin-41 during chick and mouse limb development.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein polyubiquitination	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM71

Names: RING-type E3 ubiquitin transferase TRIM71; abnormal cell LINeage LIN-41; lin-41 homolog; protein lin-41 homolog; tripartite motif containing 71, E3 ubiquitin protein ligase; tripartite motif-containing protein 71

NP_001384127.1

EC 2.3.2.27

XP_046767653.1

EC 2.3.2.27

XP_046767654.1

EC 2.3.2.27

XP_046767655.1

EC 2.3.2.27

XP_046781881.1

EC 2.3.2.27

XP_046781882.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001397198.2 → NP_001384127.1 E3 ubiquitin-protein ligase TRIM71

Status: VALIDATED

Source sequence(s)

JAENSK010000037

UniProtKB/TrEMBL

Z4YJC3

Related

ENSGALP00010025054.1, ENSGALT00010042564.1

Conserved Domains (6) summary

smart00502
Location:323 → 455

BBC; B-Box C-terminal domain

smart00557
Location:493 → 590

IG_FLMN; Filamin-type immunoglobulin domains

cd14954
Location:593 → 877

NHL_TRIM71_like; NHL repeat domain of the tripartite motif-containing protein 71 (TRIM71) and related proteins

cd16589
Location:8 → 92

RING-HC_TRIM71_C-VII; RING finger, HC subclass, found in tripartite motif-containing protein 71 (TRIM71) and similar proteins

cd19796
Location:284 → 331

Bbox2_TRIM71_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 71 (TRIM71) and similar proteins

cd19812
Location:205 → 248

Bbox1_TRIM71_C-VII; B-box-type 1 zinc finger found in tripartite motif-containing protein 71 (TRIM71) and similar proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

40434809..40490698 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046925926.1 → XP_046781882.1 E3 ubiquitin-protein ligase TRIM71 isoform X1
XM_046925925.1 → XP_046781881.1 E3 ubiquitin-protein ligase TRIM71 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

40484760..40540577 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046911697.1 → XP_046767653.1 E3 ubiquitin-protein ligase TRIM71 isoform X2

UniProtKB/TrEMBL

Z4YJC3
XM_046911699.1 → XP_046767655.1 E3 ubiquitin-protein ligase TRIM71 isoform X1
XM_046911698.1 → XP_046767654.1 E3 ubiquitin-protein ligase TRIM71 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001037275.2: Suppressed sequence

Description

NM_001037275.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.