U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SERPINE2 serpin family E member 2 [ Gallus gallus (chicken) ]

Gene ID: 424805, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
SERPINE2provided by CGNC
Official Full Name
serpin family E member 2provided by CGNC
Primary source
CGNC:3824
See related
Ensembl:ENSGALG00010025982
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SERPINE2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (7986960..8062323, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (7787954..7863324, complement)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121111504 Neighboring gene adaptor related protein complex 1 sigma 3 subunit Neighboring gene WD repeat and FYVE domain containing 1 Neighboring gene family with sequence similarity 124 member B Neighboring gene cullin 3 Neighboring gene guanylate cyclase 1, soluble, beta 4 Neighboring gene uncharacterized LOC121111503

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Analysis of chicken embryonic gonad expressed sequenced tags. Shin JH, et al. Anim Genet, 2006 Feb. PMID 16441308
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of plasminogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
glia-derived nexin
Names
plasminogen activator inhibitor type 1, member 2
serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083920.1 → NP_001077389.1  glia-derived nexin precursor

    Status: VALIDATED

    Source sequence(s)
    BX934893, CV860845
    UniProtKB/TrEMBL
    A0A8V1AA33, E1BWU2
    Related
    ENSGALP00010039124.1, ENSGALT00010063386.1
    Conserved Domains (1) summary
    cd19573
    Location:20 → 440
    serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7986960..8062323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046898389.1 → XP_046754345.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2

  2. XM_015276898.4 → XP_015132384.1  glia-derived nexin isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZZS6, A0A8V1ACC9
    Related
    ENSGALP00010039112.1, ENSGALT00010063371.1
    Conserved Domains (1) summary
    cd02051
    Location:20 → 395
    PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...

  3. XM_015276896.4 → XP_015132382.1  glia-derived nexin isoform X1

    UniProtKB/TrEMBL
    A0A8V1AA33
    Related
    ENSGALP00010039125.1, ENSGALT00010063389.1
    Conserved Domains (1) summary
    cd02051
    Location:20 → 435
    PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...

  4. XM_015276897.4 → XP_015132383.1  glia-derived nexin isoform X2

    UniProtKB/TrEMBL
    A0A1D5PLJ1, A0A8V1ACC9
    Conserved Domains (1) summary
    cd02051
    Location:20 → 402
    PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...

  5. XM_025153344.3 → XP_025009112.1  glia-derived nexin isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZZS6, A0A8V1ACC9
    Related
    ENSGALP00010039116.1, ENSGALT00010063376.1
    Conserved Domains (1) summary
    cd02051
    Location:20 → 395
    PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...

  6. XM_046898391.1 → XP_046754347.1  glia-derived nexin isoform X1

    Related
    ENSGALP00010039119.1, ENSGALT00010063380.1

  7. XM_025153343.3 → XP_025009111.1  glia-derived nexin isoform X2

    UniProtKB/TrEMBL
    A0A1D5PLJ1, A0A8V1ACC9
    Related
    ENSGALP00010039114.1, ENSGALT00010063374.1
    Conserved Domains (1) summary
    cd02051
    Location:20 → 402
    PAI-1_nexin-1; Plasminogen activator inhibitor-1_like. Plasminogen activator inhibitor-1 (PAI-1) is the primary, fast-acting inhibitor of plasminogen activators. It is often bound to vitronectin, an abundant component of the extracellular matrix in many tissues. ...

  8. XM_040705539.2 → XP_040561473.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    A0A8V1AA33, E1BWU2
    Conserved Domains (1) summary
    cd19573
    Location:20 → 440
    serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)

  9. XM_046898390.1 → XP_046754346.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2
    Related
    ENSGALP00010039121.1, ENSGALT00010063382.1

  10. XM_040705540.2 → XP_040561474.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    A0A8V1AA33, E1BWU2
    Conserved Domains (1) summary
    cd19573
    Location:20 → 440
    serpinE2_GDN; serpin family E member 2, glia derived nexin (GDN)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7787954..7863324 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046923795.1 → XP_046779751.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2

  2. XM_046923793.1 → XP_046779749.1  glia-derived nexin isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZZS6

  3. XM_046923791.1 → XP_046779747.1  glia-derived nexin isoform X1

  4. XM_046923792.1 → XP_046779748.1  glia-derived nexin isoform X2

    UniProtKB/TrEMBL
    A0A1D5PLJ1

  5. XM_046923801.1 → XP_046779757.1  glia-derived nexin isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZZS6

  6. XM_046923799.1 → XP_046779755.1  glia-derived nexin isoform X1

  7. XM_046923800.1 → XP_046779756.1  glia-derived nexin isoform X2

    UniProtKB/TrEMBL
    A0A1D5PLJ1

  8. XM_046923794.1 → XP_046779750.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2

  9. XM_046923797.1 → XP_046779753.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2

  10. XM_046923796.1 → XP_046779752.1  glia-derived nexin isoform X4

    UniProtKB/TrEMBL
    E1BWU2
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.