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TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 [ Gallus gallus (chicken) ]

Gene ID: 424562, updated on 17-Aug-2024

Summary

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Symbol
TIE1provided by CGNC
Full Name
tyrosine kinase with immunoglobulin like and EGF like domains 1provided by CGNC
Primary source
CGNC:7566
See related
Ensembl:ENSGALG00010022659
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See TIE1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (19348573..19360558)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (19355730..19367726)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054065 Neighboring gene transmembrane protein 125 Neighboring gene chromosome 1 open reading frame 210 Neighboring gene MPL proto-oncogene, thrombopoietin receptor Neighboring gene cell division cycle 20 Neighboring gene ELOVL fatty acid elongase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase receptor Tie-1
XP_015146806.2
XP_040534294.1
XP_040534295.1
XP_422400.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    19348573..19360558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291320.4 → XP_015146806.2  tyrosine-protein kinase receptor Tie-1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZR87, A0A8V0ZWV8
    Related
    ENSGALP00010033346.1, ENSGALT00010055131.1
    Conserved Domains (4) summary
    smart00060
    Location:449 → 523
    FN3; Fibronectin type 3 domain
    cd00054
    Location:234 → 259
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00063
    Location:645 → 737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05089
    Location:878 → 1174
    PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1

  2. XM_422400.8 → XP_422400.5  tyrosine-protein kinase receptor Tie-1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG3, A0A8V0ZWV8
    Related
    ENSGALP00010033370.1, ENSGALT00010055161.1
    Conserved Domains (4) summary
    smart00060
    Location:449 → 523
    FN3; Fibronectin type 3 domain
    cd00054
    Location:234 → 259
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00063
    Location:645 → 737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05089
    Location:838 → 1134
    PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    19355730..19367726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040678360.2 → XP_040534294.1  tyrosine-protein kinase receptor Tie-1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZWV8
    Conserved Domains (4) summary
    smart00060
    Location:449 → 523
    FN3; Fibronectin type 3 domain
    cd00054
    Location:234 → 259
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00063
    Location:645 → 737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05089
    Location:878 → 1174
    PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1

  2. XM_040678361.2 → XP_040534295.1  tyrosine-protein kinase receptor Tie-1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZWV8
    Conserved Domains (4) summary
    smart00060
    Location:449 → 523
    FN3; Fibronectin type 3 domain
    cd00054
    Location:234 → 259
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00063
    Location:645 → 737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05089
    Location:838 → 1134
    PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1
Nucleotide Protein
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