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FERMT2 fermitin family member 2 [ Gallus gallus (chicken) ]

Gene ID: 423589, updated on 10-Oct-2024

Summary

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Symbol
FERMT2provided by CGNC
Full Name
fermitin family member 2provided by CGNC
Primary source
CGNC:9438
See related
Ensembl:ENSGALG00010018121
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PLEKHC1
Orthologs
human mouse all
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Genomic context

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See FERMT2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (58025977..58063150, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (57900818..57938035, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene serine/threonine/tyrosine interacting protein Neighboring gene glucosamine-phosphate N-acetyltransferase 1 Neighboring gene DDHD domain containing 1 Neighboring gene uncharacterized LOC107051815

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fermitin family homolog 2
Names
pleckstrin homology domain containing, family C (with FERM domain) member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    58025977..58063150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701835.2 → XP_040557769.1  fermitin family homolog 2 isoform X7

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:263 → 346
    B41; Band 4.1 homologues
    cd01237
    Location:395 → 519
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:589 → 680
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 299
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  2. XM_040701834.2 → XP_040557768.1  fermitin family homolog 2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z661, E1C0T6
    Related
    ENSGALP00010026066.1, ENSGALT00010043824.1
    Conserved Domains (5) summary
    smart00295
    Location:263 → 346
    B41; Band 4.1 homologues
    cd01237
    Location:395 → 519
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:596 → 687
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 299
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  3. XM_004936527.5 → XP_004936584.2  fermitin family homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PU09, A0A8V0Z661
    Related
    ENSGALP00010026060.1, ENSGALT00010043814.1
    Conserved Domains (6) summary
    smart00295
    Location:274 → 357
    B41; Band 4.1 homologues
    cd01237
    Location:406 → 530
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:607 → 698
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 310
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:550 → 613
    FERM_M; FERM central domain

  4. XM_040701837.2 → XP_040557771.1  fermitin family homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0Z661, A0A8V0Z669
    Related
    ENSGALP00010026055.1, ENSGALT00010043805.1
    Conserved Domains (5) summary
    smart00295
    Location:265 → 348
    B41; Band 4.1 homologues
    cd01237
    Location:397 → 521
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:591 → 682
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 301
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  5. XM_040701833.2 → XP_040557767.1  fermitin family homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:265 → 348
    B41; Band 4.1 homologues
    cd01237
    Location:397 → 521
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:598 → 689
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 301
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  6. XM_040701832.2 → XP_040557766.1  fermitin family homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:276 → 359
    B41; Band 4.1 homologues
    cd01237
    Location:408 → 532
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:602 → 693
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 312
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  7. XM_040701831.2 → XP_040557765.1  fermitin family homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:276 → 359
    B41; Band 4.1 homologues
    cd01237
    Location:408 → 532
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:609 → 700
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 312
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  8. XM_025150868.3 → XP_025006636.1  fermitin family homolog 2 isoform X10

    UniProtKB/TrEMBL
    A0A8V0Z661
    Related
    ENSGALP00010026050.1, ENSGALT00010043797.1
    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:567 → 658
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:517 → 573
    FERM_M; FERM central domain

  9. XM_025150867.3 → XP_025006635.1  fermitin family homolog 2 isoform X9

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:578 → 669
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:528 → 584
    FERM_M; FERM central domain

  10. XM_040701836.2 → XP_040557770.1  fermitin family homolog 2 isoform X8

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:585 → 676
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  11. XM_046942614.1 → XP_046798570.1  fermitin family homolog 2 isoform X11

    Related
    ENSGALP00010026045.1, ENSGALT00010043792.1

  12. XM_046942615.1 → XP_046798571.1  fermitin family homolog 2 isoform X12

    Related
    ENSGALP00010026041.1, ENSGALT00010043786.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    57900818..57938035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040672917.2 → XP_040528851.1  fermitin family homolog 2 isoform X7

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:263 → 346
    B41; Band 4.1 homologues
    cd01237
    Location:395 → 519
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:589 → 680
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 299
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  2. XM_040672916.2 → XP_040528850.1  fermitin family homolog 2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z661, E1C0T6
    Conserved Domains (5) summary
    smart00295
    Location:263 → 346
    B41; Band 4.1 homologues
    cd01237
    Location:395 → 519
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:596 → 687
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 299
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  3. XM_040672913.2 → XP_040528847.1  fermitin family homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PU09, A0A8V0Z661
    Conserved Domains (6) summary
    smart00295
    Location:274 → 357
    B41; Band 4.1 homologues
    cd01237
    Location:406 → 530
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:607 → 698
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:39 → 118
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:119 → 310
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:550 → 613
    FERM_M; FERM central domain

  4. XM_040672921.2 → XP_040528855.1  fermitin family homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0Z661, A0A8V0Z669
    Conserved Domains (5) summary
    smart00295
    Location:265 → 348
    B41; Band 4.1 homologues
    cd01237
    Location:397 → 521
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:591 → 682
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 301
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  5. XM_040672915.2 → XP_040528849.1  fermitin family homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:265 → 348
    B41; Band 4.1 homologues
    cd01237
    Location:397 → 521
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:598 → 689
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 301
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  6. XM_040672914.2 → XP_040528848.1  fermitin family homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:276 → 359
    B41; Band 4.1 homologues
    cd01237
    Location:408 → 532
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:602 → 693
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 312
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  7. XM_040672912.2 → XP_040528846.1  fermitin family homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:276 → 359
    B41; Band 4.1 homologues
    cd01237
    Location:408 → 532
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:609 → 700
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:41 → 120
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:121 → 312
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  8. XM_040672920.2 → XP_040528854.1  fermitin family homolog 2 isoform X10

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (6) summary
    smart00295
    Location:241 → 324
    B41; Band 4.1 homologues
    cd01237
    Location:373 → 497
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:567 → 658
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 277
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:517 → 573
    FERM_M; FERM central domain

  9. XM_040672919.2 → XP_040528853.1  fermitin family homolog 2 isoform X9

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (6) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:578 → 669
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)
    pfam00373
    Location:528 → 584
    FERM_M; FERM central domain

  10. XM_040672918.2 → XP_040528852.1  fermitin family homolog 2 isoform X8

    UniProtKB/TrEMBL
    A0A8V0Z661
    Conserved Domains (5) summary
    smart00295
    Location:252 → 335
    B41; Band 4.1 homologues
    cd01237
    Location:384 → 508
    PH_fermitin; Fermitin family pleckstrin homology (PH) domain
    cd13205
    Location:585 → 676
    FERM_C_fermitin; FERM domain C-lobe of the Fermitin family
    cd17181
    Location:17 → 96
    FERM_F0_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in kindlin-2 (KIND2)
    cd17184
    Location:97 → 288
    FERM_F1_KIND2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in kindlin-2 (KIND2)

  11. XM_046919646.1 → XP_046775602.1  fermitin family homolog 2 isoform X11

Nucleotide Protein Strain
Heading Accession and Version

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