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XRCC3 X-ray repair cross complementing 3 [ Gallus gallus (chicken) ]

Gene ID: 423485, updated on 10-Oct-2024

Summary

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Symbol
XRCC3provided by CGNC
Full Name
X-ray repair cross complementing 3provided by CGNC
Primary source
CGNC:8765
See related
Ensembl:ENSGALG00010016004
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See XRCC3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (49980320..49989106, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (49958776..49967563, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene BCL2 associated athanogene 5 Neighboring gene apoptogenic 1, mitochondrial Neighboring gene kinesin light chain 1 Neighboring gene zinc finger FYVE-type containing 21 Neighboring gene protein phosphatase 1 regulatory subunit 13B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair. Sonoda E, et al. DNA Repair (Amst), 2007 Mar 1. PMID 17123873
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Role of Xrcc3 in DNA repair.
    Title: Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via synthesis-dependent strand annealing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of mitotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in t-circle formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance via recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Rad51C-XRCC3 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in replication fork IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA repair protein XRCC3
Names
X-ray repair complementing defective repair in Chinese hamster cells 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006489.2 → NP_001006489.1  DNA repair protein XRCC3

    See identical proteins and their annotated locations for NP_001006489.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000215
    UniProtKB/TrEMBL
    A0A8V0YW83, Q5ZM26
    Related
    ENSGALP00010022303.1, ENSGALT00010038551.1
    Conserved Domains (2) summary
    cd01123
    Location:82 → 344
    Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...
    pfam08423
    Location:64 → 343
    Rad51; Rad51

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    49980320..49989106 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025150795.3 → XP_025006563.1  DNA repair protein XRCC3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5NTZ0
    Related
    ENSGALP00010022302.1, ENSGALT00010038547.1
    Conserved Domains (1) summary
    cd01123
    Location:44 → 306
    Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...

  2. XM_015287481.4 → XP_015142967.1  DNA repair protein XRCC3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5NTZ0
    Conserved Domains (1) summary
    cd01123
    Location:44 → 306
    Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    49958776..49967563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046918710.1 → XP_046774666.1  DNA repair protein XRCC3 isoform X1

  2. XM_046918709.1 → XP_046774665.1  DNA repair protein XRCC3 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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