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RFX2 regulatory factor X2 [ Gallus gallus (chicken) ]

Gene ID: 420092, updated on 10-Oct-2024

Summary

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Symbol
RFX2provided by CGNC
Full Name
regulatory factor X2provided by CGNC
Primary source
CGNC:1246
See related
Ensembl:ENSGALG00010027873
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See RFX2 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (2003594..2058456, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (1569376..1624245, complement)

Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene proline rich 22 Neighboring gene La ribonucleoprotein domain family member 6 Neighboring gene uncharacterized LOC121107740 Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene MLLT1, super elongation complex subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding protein RFX2
Names
regulatory factor X, 2 (influences HLA class II expression)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2003594..2058456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015299842.3 → XP_015155328.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Related
    ENSGALP00010041304.1, ENSGALT00010067561.1
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  2. XM_040653655.2 → XP_040509589.1  DNA-binding protein RFX2 isoform X8

    UniProtKB/TrEMBL
    A0A8V1A5X3
    Related
    ENSGALP00010041297.1, ENSGALT00010067554.1

  3. XM_040653653.2 → XP_040509587.1  DNA-binding protein RFX2 isoform X5

    UniProtKB/TrEMBL
    A0A8V1ADL1, A0A8V1AG52
    Related
    ENSGALP00010041306.1, ENSGALT00010067563.1

  4. XM_004948748.5 → XP_004948805.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  5. XM_040653648.2 → XP_040509582.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  6. XM_015299845.4 → XP_015155331.1  DNA-binding protein RFX2 isoform X9

    UniProtKB/TrEMBL
    A0A8V1A5X3
    Conserved Domains (2) summary
    pfam02257
    Location:126 → 198
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 126
    RFX1_trans_act; RFX1 transcription activation region

  7. XM_015299844.4 → XP_015155330.1  DNA-binding protein RFX2 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A5X3
    Conserved Domains (2) summary
    pfam02257
    Location:151 → 223
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 126
    RFX1_trans_act; RFX1 transcription activation region

  8. XM_040653652.2 → XP_040509586.1  DNA-binding protein RFX2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AAS9, A0A8V1AG52
    Related
    ENSGALP00010041299.1, ENSGALT00010067556.1
    Conserved Domains (2) summary
    pfam02257
    Location:181 → 256
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  9. XM_046904640.1 → XP_046760596.1  DNA-binding protein RFX2 isoform X6

  10. XM_040653651.2 → XP_040509585.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  11. XM_040653650.2 → XP_040509584.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  12. XM_040653649.2 → XP_040509583.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  13. XM_040653647.2 → XP_040509581.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  14. XM_015299840.4 → XP_015155326.1  DNA-binding protein RFX2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AG48
    Related
    ENSGALP00010041295.1, ENSGALT00010067552.1
    Conserved Domains (2) summary
    pfam02257
    Location:208 → 280
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:38 → 161
    RFX1_trans_act; RFX1 transcription activation region

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1569376..1624245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040692619.2 → XP_040548553.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  2. XM_040692624.2 → XP_040548558.1  DNA-binding protein RFX2 isoform X8

    UniProtKB/TrEMBL
    A0A8V1A5X3

  3. XM_040692621.2 → XP_040548555.1  DNA-binding protein RFX2 isoform X5

    UniProtKB/TrEMBL
    A0A8V1ADL1, A0A8V1AG52

  4. XM_040692617.2 → XP_040548551.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  5. XM_040692613.2 → XP_040548547.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  6. XM_040692626.2 → XP_040548560.1  DNA-binding protein RFX2 isoform X9

    UniProtKB/TrEMBL
    A0A8V1A5X3
    Conserved Domains (2) summary
    pfam02257
    Location:126 → 198
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 126
    RFX1_trans_act; RFX1 transcription activation region

  7. XM_040692623.2 → XP_040548557.1  DNA-binding protein RFX2 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A5X3
    Conserved Domains (2) summary
    pfam02257
    Location:151 → 223
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 126
    RFX1_trans_act; RFX1 transcription activation region

  8. XM_040692620.2 → XP_040548554.1  DNA-binding protein RFX2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AAS9, A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:181 → 256
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  9. XM_046933924.1 → XP_046789880.1  DNA-binding protein RFX2 isoform X6

  10. XM_040692618.2 → XP_040548552.1  DNA-binding protein RFX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:205 → 277
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:4 → 158
    RFX1_trans_act; RFX1 transcription activation region

  11. XM_040692615.2 → XP_040548549.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  12. XM_040692614.2 → XP_040548548.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  13. XM_040692612.2 → XP_040548546.1  DNA-binding protein RFX2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG52
    Conserved Domains (2) summary
    pfam02257
    Location:209 → 281
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:8 → 162
    RFX1_trans_act; RFX1 transcription activation region

  14. XM_040692616.2 → XP_040548550.1  DNA-binding protein RFX2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AG48
    Conserved Domains (2) summary
    pfam02257
    Location:208 → 280
    RFX_DNA_binding; RFX DNA-binding domain
    pfam04589
    Location:38 → 161
    RFX1_trans_act; RFX1 transcription activation region
Nucleotide Protein
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