CD79B CD79b molecule [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CD79Bprovided by CGNC
Official Full Name: CD79b moleculeprovided by CGNC
Primary source: CGNC:147
See related: Ensembl:ENSGALG00010023621
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	27	NC_052558.1 (1273674..1278150, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	27	NC_052599.1 (2492357..2496822, complement)

Chromosome 27 - NC_052558.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate that deletion of mCD8alpha:chIgalpha (immunoglobulin-associated alpha protein)-expressing cells was specific for B cells and required active signaling downstream of the mCD8alpha:chIgalpha receptor.
Title: Negative selection of self-reactive chicken B cells requires B cell receptor signaling and is independent of the bursal microenvironment.
These results suggest that CD79B has a cis-acting regulatory element that responds to Marek's disease (MD) and probably cooperates with growth hormone in conferring genetic resistance to MD.
Title: Allele-specific expression analysis reveals CD79B has a cis-acting regulatory element that responds to Marek's disease virus infection in chickens.
Microarray analysis showed CD79B to be among the under-expressed genes in SCA-2 induced bursal cells and this was validated with qRT-PCR.
Title: Cloning and functional characterization of chicken stem cell antigen 2.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in B cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of B cell receptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: B-cell antigen receptor complex-associated protein beta chain

Names: CD79b molecule, immunoglobulin-associated beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006328.3 → NP_001006328.3 B-cell antigen receptor complex-associated protein beta chain precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000363

UniProtKB/TrEMBL

Q5ZLC0, Q8AV16

Related

ENSGALP00010034943.1, ENSGALT00010057510.1

Conserved Domains (2) summary

cd00096
Location:43 → 46

Ig; Ig strand A [structural motif]

cl11960
Location:43 → 139

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1273674..1278150 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)