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HLCS holocarboxylase synthetase [ Gallus gallus (chicken) ]

Gene ID: 418516, updated on 17-Aug-2024

Summary

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Symbol
HLCSprovided by CGNC
Full Name
holocarboxylase synthetaseprovided by CGNC
Primary source
CGNC:11987
See related
Ensembl:ENSGALG00010013104
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (106951084..107069352, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (107040350..107159130, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene claudin 14 Neighboring gene uncharacterized LOC121107509 Neighboring gene SIM bHLH transcription factor 2 Neighboring gene uncharacterized LOC121107510 Neighboring gene ripply transcriptional repressor 3 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class P

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables biotin-[acetyl-CoA-carboxylase] ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
biotin--protein ligase
Names
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
XP_015156982.1
XP_025001003.1
XP_025001007.2
XP_040515561.1
XP_040515562.1
XP_040515563.1
XP_040515564.2
XP_416725.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    106951084..107069352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025145239.3 → XP_025001007.2  biotin--protein ligase isoform X3

    UniProtKB/TrEMBL
    A0A8V0YIG6

  2. XM_416725.8 → XP_416725.1  biotin--protein ligase isoform X1

    UniProtKB/TrEMBL
    A0A8V0YIG6
    Related
    ENSGALP00010018338.1, ENSGALT00010031417.1
    Conserved Domains (2) summary
    COG0340
    Location:640 → 883
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:483 → 585
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  3. XM_025145235.3 → XP_025001003.1  biotin--protein ligase isoform X2

    UniProtKB/TrEMBL
    A0A8V0YIG6
    Conserved Domains (2) summary
    COG0340
    Location:565 → 808
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:408 → 510
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  4. XM_015301496.4 → XP_015156982.1  biotin--protein ligase isoform X4

    UniProtKB/TrEMBL
    A0A8V0YQA6
    Conserved Domains (2) summary
    COG0340
    Location:475 → 718
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:318 → 420
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    107040350..107159130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659630.2 → XP_040515564.2  biotin--protein ligase isoform X3

    UniProtKB/TrEMBL
    A0A8V0YIG6

  2. XM_040659627.2 → XP_040515561.1  biotin--protein ligase isoform X1

    UniProtKB/TrEMBL
    A0A8V0YIG6
    Conserved Domains (2) summary
    COG0340
    Location:640 → 883
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:483 → 585
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  3. XM_040659628.2 → XP_040515562.1  biotin--protein ligase isoform X2

    UniProtKB/TrEMBL
    A0A8V0YIG6
    Conserved Domains (2) summary
    COG0340
    Location:565 → 808
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:408 → 510
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  4. XM_040659629.2 → XP_040515563.1  biotin--protein ligase isoform X4

    UniProtKB/TrEMBL
    A0A8V0YQA6
    Conserved Domains (2) summary
    COG0340
    Location:475 → 718
    BirA2; Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]
    cl00020
    Location:318 → 420
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain
Nucleotide Protein
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