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SLX4 SLX4 structure-specific endonuclease subunit homolog [ Gallus gallus (chicken) ]

Gene ID: 416665, updated on 17-Aug-2024

Summary

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Official Symbol
SLX4provided by CGNC
Official Full Name
SLX4 structure-specific endonuclease subunit homologprovided by CGNC
Primary source
CGNC:5769
See related
Ensembl:ENSGALG00010016341
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
BTBD12
Orthologs
human mouse all
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Genomic context

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See SLX4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (12444459..12472469, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (12440004..12468001, complement)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054646 Neighboring gene zinc finger with KRAB and SCAN domains 7 Neighboring gene TNF receptor associated protein 1 Neighboring gene CREB binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Yamamoto KN, et al. Proc Natl Acad Sci U S A, 2011 Apr 19. PMID 21464321, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables enzyme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in meiotic DNA double-strand break processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Slx1-Slx4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
structure-specific endonuclease subunit SLX4
Names
BTB (POZ) domain containing 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12444459..12472469 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040647711.2 → XP_040503645.1  structure-specific endonuclease subunit SLX4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YNU3
    Related
    ENSGALP00010022679.1, ENSGALT00010039319.1
    Conserved Domains (1) summary
    cd18288
    Location:520 → 635
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  2. XM_015294632.4 → XP_015150118.2  structure-specific endonuclease subunit SLX4 isoform X2

    Conserved Domains (1) summary
    cd18288
    Location:642 → 757
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  3. XM_004945379.5 → XP_004945436.2  structure-specific endonuclease subunit SLX4 isoform X1

    Conserved Domains (1) summary
    cd18288
    Location:644 → 759
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  4. XM_046900728.1 → XP_046756684.1  structure-specific endonuclease subunit SLX4 isoform X1

  5. XM_015294630.4 → XP_015150116.2  structure-specific endonuclease subunit SLX4 isoform X1

    Conserved Domains (1) summary
    cd18288
    Location:644 → 759
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12440004..12468001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040684152.2 → XP_040540086.1  structure-specific endonuclease subunit SLX4 isoform X3

    Conserved Domains (1) summary
    cd18288
    Location:520 → 635
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  2. XM_040684151.2 → XP_040540085.1  structure-specific endonuclease subunit SLX4 isoform X2

    Conserved Domains (1) summary
    cd18288
    Location:642 → 757
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  3. XM_040684146.2 → XP_040540080.1  structure-specific endonuclease subunit SLX4 isoform X1

    Conserved Domains (1) summary
    cd18288
    Location:644 → 759
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  4. XM_040684150.2 → XP_040540084.1  structure-specific endonuclease subunit SLX4 isoform X1

    Conserved Domains (1) summary
    cd18288
    Location:644 → 759
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

  5. XM_040684149.2 → XP_040540083.1  structure-specific endonuclease subunit SLX4 isoform X1

    Conserved Domains (1) summary
    cd18288
    Location:644 → 759
    BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4
Nucleotide Protein Strain
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