PPP2CA protein phosphatase 2 catalytic subunit alpha [Gallus gallus (chicken)] - Gene

Summary

Symbol: PPP2CAprovided by CGNC
Full Name: protein phosphatase 2 catalytic subunit alphaprovided by CGNC
Primary source: CGNC:4870
See related: Ensembl:ENSGALG00010015861
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (15487686..15503237)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (15499503..15515054)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Suppression of Mid1 function in r2 elevates PP2Ac protein, whilst ectopic expression of Mid1 depletes PP2Ac protein.
Title: Regulation of PP2A activity by Mid1 controls cranial neural crest speed and gangliogenesis.

Submit: New GeneRIF Correction

General gene information

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Markers

Ppp2ca (e-PCR), detects polymorphism
- UniSTS:526871

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-serine dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Names: protein phosphatase 2, catalytic subunit, alpha isozyme

NP_001006152.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006152.2 → NP_001006152.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

See identical proteins and their annotated locations for NP_001006152.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000256

UniProtKB/TrEMBL

A0A8V0Y3H9, Q5ZM47

Related

ENSGALP00010022055.1, ENSGALT00010038213.1

Conserved Domains (1) summary

cd07415
Location:9 → 293

MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain