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ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 [ Gallus gallus (chicken) ]

Gene ID: 416291, updated on 17-Aug-2024

Summary

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Symbol
ADAMTS2provided by CGNC
Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 2provided by CGNC
Primary source
CGNC:4492
See related
Ensembl:ENSGALG00010015111
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ADAMTS2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
27
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (13207810..13444026)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (13221847..13457641)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene calnexin Neighboring gene leukotriene C4 synthase Neighboring gene heterogeneous nuclear ribonucleoprotein H1 Neighboring gene deoxycytidine kinase 2 Neighboring gene RUN and FYVE domain containing 1 Neighboring gene uncharacterized LOC124417179 Neighboring gene CCR4-NOT transcription complex subunit 6 Neighboring gene glutamine-fructose-6-phosphate transaminase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 2
XP_040503121.1
XP_040503123.1
XP_040503124.1
XP_040538693.1
XP_040538694.1
XP_040538695.1
XP_040538696.1
XP_414611.7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13207810..13444026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040647190.2 → XP_040503124.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:386 → 438
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:88 → 289
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:545 → 658
    ADAM_spacer1; ADAM-TS Spacer 1

  2. XM_040647187.2 → XP_040503121.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:538 → 590
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:240 → 441
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:697 → 810
    ADAM_spacer1; ADAM-TS Spacer 1

  3. XM_414611.8 → XP_414611.7  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Related
    ENSGALP00010021177.1, ENSGALT00010036399.1
    Conserved Domains (3) summary
    smart00209
    Location:538 → 590
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:240 → 441
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:697 → 810
    ADAM_spacer1; ADAM-TS Spacer 1

  4. XM_040647189.1 → XP_040503123.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:411 → 463
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:113 → 314
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:570 → 683
    ADAM_spacer1; ADAM-TS Spacer 1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13221847..13457641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682762.2 → XP_040538696.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:386 → 438
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:88 → 289
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:545 → 658
    ADAM_spacer1; ADAM-TS Spacer 1

  2. XM_040682760.2 → XP_040538694.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:538 → 590
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:240 → 441
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:697 → 810
    ADAM_spacer1; ADAM-TS Spacer 1

  3. XM_040682759.2 → XP_040538693.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:538 → 590
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:240 → 441
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:697 → 810
    ADAM_spacer1; ADAM-TS Spacer 1

  4. XM_040682761.1 → XP_040538695.1  A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJR5
    Conserved Domains (3) summary
    smart00209
    Location:411 → 463
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:113 → 314
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:570 → 683
    ADAM_spacer1; ADAM-TS Spacer 1
Nucleotide Protein
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