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ITK IL2 inducible T-cell kinase [ Gallus gallus (chicken) ]

Gene ID: 416247, updated on 17-Aug-2024

Summary

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Symbol
ITKprovided by CGNC
Full Name
IL2 inducible T-cell kinaseprovided by CGNC
Primary source
CGNC:2826
See related
Ensembl:ENSGALG00010015076
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ITK in Genome Data Viewer
Location:
chromosome: 13
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (11018301..11048463, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (11020770..11050928, complement)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase domain 19 Neighboring gene NIPA like domain containing 4 Neighboring gene cytoplasmic FMR1 interacting protein 2 Neighboring gene fibronectin type III domain containing 9 Neighboring gene mediator complex subunit 7 Neighboring gene hepatitis A virus cellular receptor 1 Neighboring gene T cell immunoglobulin and mucin domain containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in NK T cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ITK/TSK
XP_040538603.1
XP_414568.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    11018301..11048463 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_414568.7 → XP_414568.3  tyrosine-protein kinase ITK/TSK

    UniProtKB/TrEMBL
    A0A8V0YJJ1
    Related
    ENSGALP00010021097.1, ENSGALT00010036281.1
    Conserved Domains (4) summary
    cd05112
    Location:369 → 624
    PTKc_Itk; Catalytic domain of the Protein Tyrosine Kinase, Interleukin-2-inducible T-cell Kinase
    cd10396
    Location:243 → 351
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11908
    Location:185 → 240
    SH3_ITK; Src Homology 3 domain of Interleukin-2-inducible T-cell Kinase
    cd01238
    Location:18 → 159
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    11020770..11050928 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682669.2 → XP_040538603.1  tyrosine-protein kinase ITK/TSK

    UniProtKB/TrEMBL
    A0A8V0YJJ1
    Conserved Domains (4) summary
    cd05112
    Location:369 → 624
    PTKc_Itk; Catalytic domain of the Protein Tyrosine Kinase, Interleukin-2-inducible T-cell Kinase
    cd10396
    Location:243 → 351
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11908
    Location:185 → 240
    SH3_ITK; Src Homology 3 domain of Interleukin-2-inducible T-cell Kinase
    cd01238
    Location:18 → 159
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
Nucleotide Protein
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