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NSD1 nuclear receptor binding SET domain protein 1 [ Gallus gallus (chicken) ]

Gene ID: 416214, updated on 17-Aug-2024

Summary

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Official Symbol
NSD1provided by CGNC
Official Full Name
nuclear receptor binding SET domain protein 1provided by CGNC
Primary source
CGNC:2147
See related
Ensembl:ENSGALG00010009567
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See NSD1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (9817081..9877796, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (9819444..9880174, complement)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene PRELI domain containing 1 Neighboring gene RAB24, member RAS oncogene family Neighboring gene fibroblast growth factor receptor 4 Neighboring gene zinc finger protein 346

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K36 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; histone-lysine N-methyltransferase, H3 lysine-36 specific
XP_040503220.1
XP_040503221.1
XP_040539030.1
XP_040539031.1
XP_046756387.1
XP_046783134.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9817081..9877796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046900431.1 → XP_046756387.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X2

  2. XM_040647286.2 → XP_040503220.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2K5
    Related
    ENSGALP00010013183.1, ENSGALT00010022807.1
    Conserved Domains (10) summary
    cd05838
    Location:1651 → 1745
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1788 → 1838
    AWS; associated with SET domains
    PHA03247
    Location:2133 → 2705
    PHA03247; large tegument protein UL36; Provisional
    cd15648
    Location:1442 → 1484
    PHD1_NSD1_2; PHD finger 1 found in nuclear receptor-binding SET domain-containing protein NSD1 and NSD2
    cd15650
    Location:1489 → 1535
    PHD2_NSD1; PHD finger 2 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15653
    Location:1536 → 1589
    PHD3_NSD1; PHD finger 3 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15656
    Location:1606 → 1645
    PHD4_NSD1; PHD finger 4 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15659
    Location:2017 → 2059
    PHD5_NSD1; PHD finger 5 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd19210
    Location:1838 → 1979
    SET_NSD1; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 1 (NSD1) and similar proteins
    cl02554
    Location:205 → 314
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  3. XM_040647287.2 → XP_040503221.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y2K5
    Conserved Domains (10) summary
    cd05838
    Location:1651 → 1745
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1788 → 1838
    AWS; associated with SET domains
    PHA03247
    Location:2133 → 2705
    PHA03247; large tegument protein UL36; Provisional
    cd15648
    Location:1442 → 1484
    PHD1_NSD1_2; PHD finger 1 found in nuclear receptor-binding SET domain-containing protein NSD1 and NSD2
    cd15650
    Location:1489 → 1535
    PHD2_NSD1; PHD finger 2 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15653
    Location:1536 → 1589
    PHD3_NSD1; PHD finger 3 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15656
    Location:1606 → 1645
    PHD4_NSD1; PHD finger 4 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15659
    Location:2017 → 2059
    PHD5_NSD1; PHD finger 5 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd19210
    Location:1838 → 1979
    SET_NSD1; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 1 (NSD1) and similar proteins
    cl02554
    Location:205 → 314
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    9819444..9880174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046927178.1 → XP_046783134.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X3

  2. XM_040683096.2 → XP_040539030.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1

    Conserved Domains (10) summary
    cd05838
    Location:1651 → 1745
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1788 → 1838
    AWS; associated with SET domains
    PHA03247
    Location:2133 → 2705
    PHA03247; large tegument protein UL36; Provisional
    cd15648
    Location:1442 → 1484
    PHD1_NSD1_2; PHD finger 1 found in nuclear receptor-binding SET domain-containing protein NSD1 and NSD2
    cd15650
    Location:1489 → 1535
    PHD2_NSD1; PHD finger 2 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15653
    Location:1536 → 1589
    PHD3_NSD1; PHD finger 3 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15656
    Location:1606 → 1645
    PHD4_NSD1; PHD finger 4 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15659
    Location:2017 → 2059
    PHD5_NSD1; PHD finger 5 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd19210
    Location:1838 → 1979
    SET_NSD1; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 1 (NSD1) and similar proteins
    cl02554
    Location:205 → 314
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

  3. XM_040683097.2 → XP_040539031.1  histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1

    Conserved Domains (10) summary
    cd05838
    Location:1651 → 1745
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1788 → 1838
    AWS; associated with SET domains
    PHA03247
    Location:2133 → 2705
    PHA03247; large tegument protein UL36; Provisional
    cd15648
    Location:1442 → 1484
    PHD1_NSD1_2; PHD finger 1 found in nuclear receptor-binding SET domain-containing protein NSD1 and NSD2
    cd15650
    Location:1489 → 1535
    PHD2_NSD1; PHD finger 2 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15653
    Location:1536 → 1589
    PHD3_NSD1; PHD finger 3 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15656
    Location:1606 → 1645
    PHD4_NSD1; PHD finger 4 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd15659
    Location:2017 → 2059
    PHD5_NSD1; PHD finger 5 found in nuclear receptor-binding SET domain-containing protein 1 (NSD1)
    cd19210
    Location:1838 → 1979
    SET_NSD1; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 1 (NSD1) and similar proteins
    cl02554
    Location:205 → 314
    PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
Nucleotide Protein Strain
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