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CG7488 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41597, updated on 2-Nov-2024

Summary

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Official Symbol
CG7488provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038106
Locus tag
Dmel_CG7488
See related
AllianceGenome:FB:FBgn0038106
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7488
Summary
Predicted to enable rRNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in ribosomal small subunit assembly. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in Perrault syndrome 6. Orthologous to human ERAL1 (Era like 12S mitochondrial rRNA chaperone 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG7488 in Genome Data Viewer
Location:
87D7-87D7; 3-53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12995620..12996925)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8821342..8822647)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene yellow-f Neighboring gene yellow-f2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-scale analysis of positionally relocated genes. Bhutkar A, et al. Genome Res, 2007 Dec. PMID 17989252, Free PMC Article
  2. Combining mapping and arraying: An approach to candidate gene identification. Wayne ML, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12415114, Free PMC Article
  3. Genes Relocated Between Drosophila Chromosome Arms Evolve Under Relaxed Selective Constraints Relative to Non-Relocated Genes. Hart MLI, et al. J Mol Evol, 2018 Jul. PMID 29926120
  4. Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators. Pennemann FL, et al. Nat Commun, 2021 Dec 1. PMID 34853303, Free PMC Article
  5. Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing. Sutton DC, et al. PLoS One, 2024. PMID 38412189, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosomal small subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7488-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12995620..12996925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141991.3 → NP_650248.1  uncharacterized protein Dmel_CG7488 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650248.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VG07
    Related
    FBpp0082163
    Conserved Domains (2) summary
    cd04163
    Location:57 → 259
    Era; E. coli Ras-like protein (Era) is a multifunctional GTPase
    COG1159
    Location:55 → 362
    Era; GTPase Era, involved in 16S rRNA processing [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VG07 Q9VG07

Gene LinkOut

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