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MAPK4 mitogen-activated protein kinase 4 [ Gallus gallus (chicken) ]

Gene ID: 415419, updated on 10-Oct-2024

Summary

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Symbol
MAPK4provided by CGNC
Full Name
mitogen-activated protein kinase 4provided by CGNC
Primary source
CGNC:49976
See related
Ensembl:ENSGALG00010020989
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MAPK6
Orthologs
human mouse all
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Genomic context

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See MAPK4 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (8942477..9011479, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (8814501..8889314, complement)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene BCL2 like 10 Neighboring gene uncharacterized LOC121111646 Neighboring gene uncharacterized LOC121111580 Neighboring gene LEO1 homolog, Paf1/RNA polymerase II complex component Neighboring gene tropomodulin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase 6
Names
MAP kinase 6
MAPK 6
NP_001025720.1
XP_015147391.1
XP_015147392.1
XP_015147394.1
XP_015147395.1
XP_015147396.1
XP_015147397.1
XP_025009600.1
XP_040562235.1
XP_040562236.1
XP_040562237.1
XP_040562238.1
XP_040562240.1
XP_046754975.1
XP_046754976.1
XP_046754977.1
XP_046754978.1
XP_046754979.1
XP_046754980.1
XP_046754981.1
XP_046754982.1
XP_046754983.1
XP_046754984.1
XP_046754985.1
XP_046754986.1
XP_046754987.1
XP_046754988.1
XP_046780733.1
XP_046780734.1
XP_046780735.1
XP_046780736.1
XP_046780737.1
XP_046780738.1
XP_046780739.1
XP_046780740.1
XP_046780741.1
XP_046780742.1
XP_046780743.1
XP_046780744.1
XP_046780745.1
XP_046780746.1
XP_046780747.1
XP_046780748.1
XP_046780749.1
XP_046780750.1
XP_046780751.1
XP_046780752.1
XP_046780753.1
XP_046780754.1
XP_046780755.1
XP_046780756.1
XP_046780757.1
XP_046780758.1
XP_046780759.1
XP_046780760.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030549.2 → NP_001025720.1  mitogen-activated protein kinase 6

    See identical proteins and their annotated locations for NP_001025720.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000245
    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8942477..9011479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025153832.3 → XP_025009600.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  2. XM_040706304.2 → XP_040562238.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  3. XM_040706306.2 → XP_040562240.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  4. XM_015291906.4 → XP_015147392.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  5. XM_015291908.4 → XP_015147394.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  6. XM_046899023.1 → XP_046754979.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  7. XM_040706301.2 → XP_040562235.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  8. XM_046899029.1 → XP_046754985.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  9. XM_046899028.1 → XP_046754984.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  10. XM_046899019.1 → XP_046754975.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  11. XM_046899027.1 → XP_046754983.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  12. XM_046899026.1 → XP_046754982.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  13. XM_046899025.1 → XP_046754981.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  14. XM_046899022.1 → XP_046754978.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  15. XM_046899021.1 → XP_046754977.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  16. XM_046899020.1 → XP_046754976.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  17. XM_046899024.1 → XP_046754980.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  18. XM_046899032.1 → XP_046754988.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  19. XM_046899031.1 → XP_046754987.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  20. XM_040706302.2 → XP_040562236.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  21. XM_015291905.4 → XP_015147391.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  22. XM_015291910.4 → XP_015147396.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  23. XM_015291911.4 → XP_015147397.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  24. XM_015291909.4 → XP_015147395.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  25. XM_040706303.2 → XP_040562237.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    UniProtKB/TrEMBL
    A0A8V0ZGP5
    Conserved Domains (1) summary
    cd07854
    Location:14 → 355
    STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

  26. XM_046899030.1 → XP_046754986.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
    Related
    ENSGALP00010029958.1, ENSGALT00010050735.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8814501..8889314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924793.1 → XP_046780749.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  2. XM_046924792.1 → XP_046780748.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  3. XM_046924801.1 → XP_046780757.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  4. XM_046924804.1 → XP_046780760.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  5. XM_046924778.1 → XP_046780734.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  6. XM_046924780.1 → XP_046780736.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  7. XM_046924785.1 → XP_046780741.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  8. XM_046924781.1 → XP_046780737.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  9. XM_046924796.1 → XP_046780752.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  10. XM_046924794.1 → XP_046780750.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  11. XM_046924782.1 → XP_046780738.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  12. XM_046924791.1 → XP_046780747.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  13. XM_046924795.1 → XP_046780751.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  14. XM_046924790.1 → XP_046780746.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  15. XM_046924788.1 → XP_046780744.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  16. XM_046924784.1 → XP_046780740.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  17. XM_046924783.1 → XP_046780739.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  18. XM_046924789.1 → XP_046780745.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  19. XM_046924787.1 → XP_046780743.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  20. XM_046924803.1 → XP_046780759.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  21. XM_046924802.1 → XP_046780758.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  22. XM_046924797.1 → XP_046780753.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  23. XM_046924777.1 → XP_046780733.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  24. XM_046924798.1 → XP_046780754.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  25. XM_046924799.1 → XP_046780755.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  26. XM_046924779.1 → XP_046780735.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  27. XM_046924786.1 → XP_046780742.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3

  28. XM_046924800.1 → XP_046780756.1  mitogen-activated protein kinase 6 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3W3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5F3W3.1 GenPept UniProtKB/Swiss-Prot:Q5F3W3

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