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CDH13 cadherin 13 [ Gallus gallus (chicken) ]

Gene ID: 414849, updated on 10-Oct-2024

Summary

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Symbol
CDH13provided by CGNC
Full Name
cadherin 13provided by CGNC
Primary source
CGNC:4087
See related
Ensembl:ENSGALG00010007529
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
cadherin-13
Orthologs
human mouse all
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Genomic context

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See CDH13 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (15611499..16044434)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (15958572..16391622)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054316 Neighboring gene uncharacterized LOC112533250 Neighboring gene uncharacterized LOC112533251 Neighboring gene malonyl-CoA decarboxylase Neighboring gene heat shock factor binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide association analysis of avian resistance to Campylobacter jejuni colonization identifies risk locus spanning the CDH13 gene. Connell S, et al. G3 (Bethesda), 2013 May 20. PMID 23550144, Free PMC Article
  2. T-cadherin 2: molecular characterization, function in cell adhesion, and coexpression with T-cadherin and N-cadherin. Sacristán MP, et al. J Neurosci Res, 1993 Apr 15. PMID 8315665
  3. T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo. Ranscht B, et al. Development, 1991 Jan. PMID 1707785
  4. T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region. Ranscht B, et al. Neuron, 1991 Sep. PMID 1654948
  5. Glycosyl phosphatidylinositol--anchored T-cadherin mediates calcium-dependent, homophilic cell adhesion. Vestal DJ, et al. J Cell Biol, 1992 Oct. PMID 1400585, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A risk locus with genome-wide significance spanning the T-cadherin (CDH13) gene for resistance to C. jejuni colonization in the avian intestine, is reported.
    Title: Genome-wide association analysis of avian resistance to Campylobacter jejuni colonization identifies risk locus spanning the CDH13 gene.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adherens junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin-13
Names
T-cad
T-cadherin
cadherin 13, H-cadherin (heart)
NP_001001760.2
NP_001383215.1
XP_015148007.1
XP_040562950.2
XP_040562951.2
XP_040562953.1
XP_046755346.1
XP_046781336.1
XP_046781337.1
XP_046781338.1
XP_046781339.1
XP_046781340.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001760.2 → NP_001001760.2  cadherin-13 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000248
    UniProtKB/TrEMBL
    A0A8V0Y0Z2
    Related
    ENSGALP00010009884.1, ENSGALT00010017957.1
    Conserved Domains (4) summary
    cd11304
    Location:481 → 581
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam00028
    Location:144 → 236
    Cadherin; Cadherin domain
    pfam08758
    Location:26 → 112
    Cadherin_pro; Cadherin prodomain like
    cl29226
    Location:600 → 680
    Cadherin; Cadherin domain

  2. NM_001396286.1 → NP_001383215.1  cadherin-13 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000248
    UniProtKB/Swiss-Prot
    P33150, Q91353
    UniProtKB/TrEMBL
    A0A8V0Y0Z2
    Related
    ENSGALP00010009887.1, ENSGALT00010017961.1
    Conserved Domains (4) summary
    cd11304
    Location:481 → 581
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam00028
    Location:144 → 236
    Cadherin; Cadherin domain
    pfam08758
    Location:26 → 112
    Cadherin_pro; Cadherin prodomain like
    cl29226
    Location:600 → 680
    Cadherin; Cadherin domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15611499..16044434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015292521.4 → XP_015148007.1  cadherin-13 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XXX5
    Conserved Domains (4) summary
    cd11304
    Location:482 → 582
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam00028
    Location:145 → 237
    Cadherin; Cadherin domain
    pfam08758
    Location:27 → 113
    Cadherin_pro; Cadherin prodomain like
    cl09101
    Location:601 → 681
    E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

  2. XM_046899390.1 → XP_046755346.1  cadherin-13 isoform X4

    Related
    ENSGALP00010009879.1, ENSGALT00010017952.1

  3. XM_040707017.2 → XP_040562951.2  cadherin-13 isoform X2

  4. XM_040707016.2 → XP_040562950.2  cadherin-13 isoform X1

  5. XM_040707019.2 → XP_040562953.1  cadherin-13 isoform X5

    Conserved Domains (2) summary
    cd11304
    Location:309 → 409
    Cadherin_repeat; Cadherin tandem repeat domain
    cl29226
    Location:434 → 508
    Cadherin; Cadherin domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15958572..16391622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925382.1 → XP_046781338.1  cadherin-13 isoform X3

  2. XM_046925383.1 → XP_046781339.1  cadherin-13 isoform X4

  3. XM_046925381.1 → XP_046781337.1  cadherin-13 isoform X2

  4. XM_046925380.1 → XP_046781336.1  cadherin-13 isoform X1

  5. XM_046925384.1 → XP_046781340.1  cadherin-13 isoform X5

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P33150.1 GenPept UniProtKB/Swiss-Prot:P33150

Gene LinkOut

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