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eea1.S early endosome antigen 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 414564, updated on 4-Nov-2024

Summary

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Official Symbol
eea1.S
Official Full Name
early endosome antigen 1 S homeolog
Primary source
Xenbase:XB-GENE-865932
Locus tag
XELAEV_18021234mg
See related
EnsemblRapid:ENSXLAG00005022049 AllianceGenome:Xenbase:XB-GENE-865932
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
eea1
Summary
Predicted to enable 1-phosphatidylinositol binding activity and metal ion binding activity. Predicted to act upstream of or within endocytosis. Predicted to be located in early endosome. Orthologous to human EEA1 (early endosome antigen 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eea1.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
31
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (91648047..91693406)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (89816065..89861511)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 N S homeolog Neighboring gene nudix hydrolase 4 S homeolog Neighboring gene pleckstrin homology and RhoGEF domain containing G7 S homeolog Neighboring gene B-cell translocation gene 1, anti-proliferative S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 1-phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in early endosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
early endosome antigen 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    91648047..91693406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018256016.2 → XP_018111505.1  early endosome antigen 1 isoform X2

    UniProtKB/TrEMBL
    A0A8J0UXR3
    Related
    ENSXLAP00005065151.1, ENSXLAT00005066668.1

  2. XM_018256015.2 → XP_018111504.1  early endosome antigen 1 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GUQ2, A0A974D8U6
    Related
    ENSXLAP00005065351.1, ENSXLAT00005066867.1

  3. XM_018256017.2 → XP_018111506.1  early endosome antigen 1 isoform X2

    UniProtKB/TrEMBL
    A0A8J0UXR3

  4. XM_041588634.1 → XP_041444568.1  early endosome antigen 1 isoform X3

    UniProtKB/TrEMBL
    A0A8J1MT93
    Related
    ENSXLAP00005065067.1, ENSXLAT00005066582.1
    Conserved Domains (3) summary
    COG1196
    Location:207 → 965
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:5 → 301
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15730
    Location:1237 → 1299
    FYVE_EEA1; FYVE domain found in early endosome antigen 1 (EEA1) and similar proteins

  5. XM_018256018.2 → XP_018111507.1  early endosome antigen 1 isoform X4

    UniProtKB/TrEMBL
    A0A8J0UWS3
Nucleotide Protein Strain
Heading Accession and Version

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