KRT6A keratin 6A [Gallus gallus (chicken)] - Gene

Summary

Gene symbol: KRT6A
Gene description: keratin 6A
See related: Ensembl:ENSGALG00010024140
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

Location:: chromosome: 34

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	34	NC_052565.1 (2048044..2053178)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	34	NC_052606.1 (1896668..1901804)

Chromosome 34 - NC_052565.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

we identify the molecular basis of the distinctive frizzle (F) feather phenotype that is caused by a single autosomal incomplete dominant gene (alpha-keratin-75) in which heterozygous individuals show less severe phenotypes than homozygous individuals.
Title: The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables structural constituent of skin epidermis	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intermediate filament organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in keratinization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in keratin filament	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: keratin 6A

Names: type II alpha-keratin IIC

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001313.3 → NP_001001313.3 keratin 6A

Status: VALIDATED

Source sequence(s)

JAENSK010000492

UniProtKB/TrEMBL

A0A146F047, A0A146F050

Related

ENSGALP00010035848.1, ENSGALT00010058883.1

Conserved Domains (2) summary

pfam00038
Location:136 → 449

Filament; Intermediate filament protein

pfam16208
Location:15 → 133

Keratin_2_head; Keratin type II head