IGFBP1 insulin like growth factor binding protein 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: IGFBP1provided by CGNC
Full Name: insulin like growth factor binding protein 1provided by CGNC
Primary source: CGNC:49889
See related: Ensembl:ENSGALG00010008417
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (54589779..54595974)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (54522635..54528848)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables insulin-like growth factor I binding	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin-like growth factor II binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of insulin-like growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: insulin-like growth factor-binding protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001294.2 → NP_001001294.2 insulin-like growth factor-binding protein 1 isoform 1 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000039

UniProtKB/TrEMBL

Q6PN72

Related

ENSGALP00010011676.1, ENSGALT00010020128.1

Conserved Domains (2) summary

smart00121
Location:36 → 112

IB; Insulin growth factor-binding protein homologues

cd00191
Location:188 → 264

TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
NM_001396563.1 → NP_001383492.1 insulin-like growth factor-binding protein 1 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000039

UniProtKB/TrEMBL

A0A8V0XTW7

Related

ENSGALP00010011679.1, ENSGALT00010020131.1

Conserved Domains (2) summary

smart00121
Location:36 → 112

IB; Insulin growth factor-binding protein homologues

cl00150
Location:188 → 229

TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases