U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

capn7 calpain 7 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 407932, updated on 4-Nov-2024

Summary

Official Symbol
capn7provided by Xenbase
Official Full Name
calpain 7provided by Xenbase
Primary source
Xenbase:XB-GENE-996630
See related
Ensembl:ENSXETG00000012554 AllianceGenome:Xenbase:XB-GENE-996630
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Orthologous to human CAPN7 (calpain 7). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See capn7 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
22
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (51575637..51610167, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (72589979..72626029)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene methyltransferase 6, tRNA N3-cytidine Neighboring gene SH3-domain binding protein 5 Neighboring gene collagen type VI alpha 5 chain Neighboring gene collagen, type VI, alpha 6

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213688.2NP_998853.1  calpain-7

    See identical proteins and their annotated locations for NP_998853.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067919
    UniProtKB/TrEMBL
    A0A6I8RPQ8, Q6NVT4
    Conserved Domains (4) summary
    smart00720
    Location:646766
    calpain_III; calpain_III domain
    cd00044
    Location:170494
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02680
    Location:41113
    MIT_calpain7_2; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:132
    MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    51575637..51610167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012964502.3XP_012819956.2  calpain-7 isoform X1

    UniProtKB/TrEMBL
    A0A6I8QT93, A0A6I8RPQ8
    Related
    ENSXETP00000072839.2, ENSXETT00000081025.2
    Conserved Domains (4) summary
    smart00720
    Location:697817
    calpain_III; calpain_III domain
    cd00044
    Location:221545
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02680
    Location:92164
    MIT_calpain7_2; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:1383
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  2. XM_031903305.1XP_031759165.1  calpain-7 isoform X4

    UniProtKB/TrEMBL
    A0A6I8RPQ8, A0A8J1JQ54
    Conserved Domains (4) summary
    smart00720
    Location:596716
    calpain_III; calpain_III domain
    cd00044
    Location:214538
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02680
    Location:85157
    MIT_calpain7_2; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:576
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  3. XM_012964503.3XP_012819957.2  calpain-7 isoform X2

    UniProtKB/TrEMBL
    A0A6I8R8L3, A0A6I8RPQ8
    Related
    ENSXETP00000076986.2, ENSXETT00000093452.2
    Conserved Domains (4) summary
    smart00720
    Location:690810
    calpain_III; calpain_III domain
    cd00044
    Location:214538
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02680
    Location:85157
    MIT_calpain7_2; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:576
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  4. XM_018094608.2XP_017950097.2  calpain-7 isoform X3

    UniProtKB/TrEMBL
    A0A6I8RPQ8, A0A8J0SUE6
    Conserved Domains (2) summary
    smart00720
    Location:537657
    calpain_III; calpain_III domain
    cd00044
    Location:61385
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.