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MIR30C2 microRNA 30c-2 [ Homo sapiens (human) ]

Gene ID: 407032, updated on 17-Sep-2024

Summary

Official Symbol
MIR30C2provided by HGNC
Official Full Name
microRNA 30c-2provided by HGNC
Primary source
HGNC:HGNC:31627
See related
Ensembl:ENSG00000199094 miRBase:MI0000254; AllianceGenome:HGNC:31627
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIRN30C2; mir-30c-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR30C2 in Genome Data Viewer
Location:
6q13
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (71376960..71377031, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (72557564..72557635, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (72086663..72086734, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901339 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:71961178-71961445 Neighboring gene coiled-coil domain containing 112 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17326 Neighboring gene opioid growth factor receptor like 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:72077050-72078249 Neighboring gene origin of replication 343 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:72111792-72112320 Neighboring gene long intergenic non-protein coding RNA 472 Neighboring gene microRNA 30a

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_029598.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL136164
    Related
    ENST00000362224.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    71376960..71377031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    72557564..72557635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)