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serinc5 serine incorporator 5 [ Danio rerio (zebrafish) ]

Gene ID: 406835, updated on 12-Sep-2024

Summary

Official Symbol
serinc5provided by ZNC
Official Full Name
serine incorporator 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2918
See related
Ensembl:ENSDARG00000008153 AllianceGenome:ZFIN:ZDB-GENE-040426-2918
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb651; zgc:55396; wu:fb37d09
Summary
Predicted to be involved in defense response to virus; detection of virus; and innate immune response. Predicted to act upstream of or within several processes, including myelination; phospholipid metabolic process; and sphingolipid metabolic process. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in several structures, including central nervous system; hindbrain neural plate; midbrain hindbrain boundary neural keel; optic primordium; and optic vesicle. Orthologous to human SERINC5 (serine incorporator 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See serinc5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (51949725..51998471, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (51303132..51351878, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene metaxin 3 Neighboring gene thrombospondin 4a Neighboring gene si:ch211-198e13.3 Neighboring gene cyclin-dependent kinase 7

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within defense response to virus IEA
Inferred from Electronic Annotation
more info
 
involved_in defense response to virus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in detection of virus ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213514.1NP_998679.1  serine incorporator 5

    See identical proteins and their annotated locations for NP_998679.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044159
    UniProtKB/Swiss-Prot
    B2GT27, G1K2T1, Q6IQA9, Q803X0
    Related
    ENSDARP00000087966.4, ENSDART00000097194.5
    Conserved Domains (1) summary
    pfam03348
    Location:13458
    Serinc; Serine incorporator (Serinc)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    51949725..51998471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)