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aebp2 AE binding protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 406815, updated on 2-Nov-2024

Summary

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Official Symbol
aebp2provided by ZNC
Official Full Name
AE binding protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2885
See related
Ensembl:ENSDARG00000006038 AllianceGenome:ZFIN:ZDB-GENE-040426-2885
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63755; wu:fk42f11; wu:fk52h12
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex. Orthologous to human AEBP2 (AE binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See aebp2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (2927270..2945327, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (2997159..3015216, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family, member 1C1 Neighboring gene phosphodiesterase 3A, cGMP-inhibited Neighboring gene pleckstrin homology domain containing, family A member 5 Neighboring gene uncharacterized LOC137491498 Neighboring gene intestine-specific homeobox

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ESC/E(Z) complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ESC/E(Z) complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein AEBP2
Names
AE-binding protein 2 homolog
adipocyte enhancer-binding protein 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213494.2 → NP_998659.2  zinc finger protein AEBP2

    See identical proteins and their annotated locations for NP_998659.2

    Status: VALIDATED

    Source sequence(s)
    BX914207
    UniProtKB/Swiss-Prot
    Q1LUY9, Q1LUZ0, Q7SXV2
    Related
    ENSDARP00000022060.7, ENSDART00000019518.8
    Conserved Domains (3) summary
    COG5048
    Location:135 → 257
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:184 → 204
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:233 → 259
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    2927270..2945327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068219578.1 → XP_068075679.1  zinc finger protein AEBP2 isoform X1

    Related
    ENSDARP00000106888.2, ENSDART00000128934.4
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7SXV2.2 GenPept UniProtKB/Swiss-Prot:Q7SXV2

Gene LinkOut

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