zbtb2b zinc finger and BTB domain containing 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zbtb2bprovided by ZNC
Official Full Name: zinc finger and BTB domain containing 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2753
See related: Ensembl:ENSDARG00000028086 AllianceGenome:ZFIN:ZDB-GENE-040426-2753
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zbtb2; fc05d08; fc26d04; zgc:56572; wu:fc05d08; wu:fc26d04; CH73-109I14.4
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. Is expressed in several structures, including alar plate midbrain region; immature eye; optic tectum; vasculature; and ventral mesoderm. Orthologous to human ZBTB2 (zinc finger and BTB domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 20

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (26394699..26407233)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (26495609..26508143)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fc26d04.x1 (e-PCR)
- UniSTS:193305

fc05d08.x1 (e-PCR)
- UniSTS:192208

fc05d08.x1 (e-PCR)
- UniSTS:192209

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cytokine production	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: zinc finger and BTB domain-containing protein 2b

Names: zinc finger and BTB domain containing 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213415.2 → NP_998580.2 zinc finger and BTB domain-containing protein 2b

Status: PROVISIONAL

Source sequence(s)

BC074064

UniProtKB/TrEMBL

A0A8M1PPY8, F2Z4W3, Q6GMI4

Related

ENSDARP00000072556.4, ENSDART00000078093.6

Conserved Domains (5) summary

smart00225
Location:25 → 85

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00017
Location:383 → 403

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:381 → 403

zf-C2H2; Zinc finger, C2H2 type

pfam00651
Location:14 → 112

BTB; BTB/POZ domain

pfam13465
Location:395 → 417

zf-H2C2_2; Zinc-finger double domain