tdh L-threonine dehydrogenase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tdhprovided by ZNC
Official Full Name: L-threonine dehydrogenaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2379
See related: Ensembl:ENSDARG00000002745 AllianceGenome:ZFIN:ZDB-GENE-040426-2379
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:77667; wu:fc11b08
Summary: Predicted to enable L-threonine 3-dehydrogenase activity. Predicted to be involved in threonine catabolic process. Is expressed in several structures, including immature eye; mucus secreting cell; nervous system; neural rod; and pancreas. Orthologous to human TDH (L-threonine dehydrogenase (pseudogene)). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (18992679..18998022)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (19093045..19098439)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc54c01.y1 (e-PCR)
- UniSTS:194058

fc11b08.x1 (e-PCR)
- UniSTS:192496

fc11b08.x1 (e-PCR)
- UniSTS:192497

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables L-threonine 3-dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-threonine 3-dehydrogenase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in threonine catabolic process	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: L-threonine dehydrogenase

NP_998410.1

EC 1.1.1.103

XP_005160513.1

EC 1.1.1.103

XP_068071509.1

EC 1.1.1.103

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213245.1 → NP_998410.1 L-threonine dehydrogenase

See identical proteins and their annotated locations for NP_998410.1

Status: PROVISIONAL

Source sequence(s)

BC063962

UniProtKB/TrEMBL

A0A8M1PPF7, Q6P3J8

Related

ENSDARP00000024225.5, ENSDART00000025509.7

Conserved Domains (2) summary

cd05272
Location:59 → 365

TDH_SDR_e; L-threonine dehydrogenase, extended (e) SDRs

COG0451
Location:74 → 371

WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]