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laf labial associated factor [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40606, updated on 18-Sep-2024

Summary

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Official Symbol
lafprovided by FlyBase
Official Full Name
labial associated factorprovided by FlyBase
Primary source
FLYBASE:FBgn0020280
Locus tag
Dmel_CG14660
See related
AllianceGenome:FB:FBgn0020280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
C6; CG14660; Dmel\CG14660
Orthologs
all
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Genomic context

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See laf in Genome Data Viewer
Location:
82E1-82E1; 3-47.1 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4876005..4878533, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (701727..704255, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene odd paired Neighboring gene long non-coding RNA:CR45580 Neighboring gene Germ line transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Peng JC, et al. Nat Genet, 2016 Mar. PMID 26780607, Free PMC Article
  2. Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Moshkin YM, et al. Mol Cell, 2009 Sep 24. PMID 19782028
  3. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
  4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  

General protein information

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Preferred Names
labial associated factor
Names
CG14660-PA
CG14660-PB
clone C6
laf-PA
laf-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4876005..4878533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141247.1 → NP_649504.1  labial associated factor, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649504.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T8Z9, Q9VN67
    Related
    FBpp0078492, FBtr0078852

  2. NM_001300236.1 → NP_001287165.1  labial associated factor, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287165.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LGL3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LGL3 A0A0B4LGL3
Q8T8Z9 Q8T8Z9

Gene LinkOut

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