eif2ak3.S eukaryotic translation initiation factor 2 alpha kinase 3 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: eif2ak3.S
Official Full Name: eukaryotic translation initiation factor 2 alpha kinase 3 S homeolog
Primary source: Xenbase:XB-GENE-989852
Locus tag: XELAEV_18008835mg
See related: EnsemblRapid:ENSXLAG00005000821 AllianceGenome:Xenbase:XB-GENE-989852
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: eif2ak3
Summary: Predicted to enable ATP binding activity; eukaryotic translation initiation factor 2alpha kinase activity; and translation initiation factor activity. Predicted to act upstream of or within several processes, including protein phosphorylation; response to unfolded protein; and translational initiation. Predicted to be located in endoplasmic reticulum and nucleus. Human ortholog(s) of this gene implicated in Wolcott-Rallison syndrome and type 1 diabetes mellitus. Orthologous to human EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (9469734..9514966, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (9350817..9396304, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables eukaryotic translation initiation factor 2alpha kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to endoplasmic reticulum stress	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to unfolded protein	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain

XM_018242993.2 → XP_018098482.1 eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2

UniProtKB/TrEMBL

A0A8J0U7L7
XM_018242992.2 → XP_018098481.1 eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1

UniProtKB/TrEMBL

A0A8J0UAD4

Related

ENSXLAP00005002427.1, ENSXLAT00005002473.1
XM_018242994.2 → XP_018098483.1 eukaryotic translation initiation factor 2-alpha kinase 3 isoform X3

UniProtKB/TrEMBL

A0A1L8HKK4, A0A974DTN5

Related

ENSXLAP00005002431.1, ENSXLAT00005002477.1