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Mettl21e methyltransferase like 21E [ Mus musculus (house mouse) ]

Gene ID: 403183, updated on 14-Nov-2024

Summary

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Official Symbol
Mettl21eprovided by MGI
Official Full Name
methyltransferase like 21Eprovided by MGI
Primary source
MGI:MGI:2685837
See related
Ensembl:ENSMUSG00000046828 AllianceGenome:MGI:2685837
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm991; 4832428D23Rik
Summary
Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in methylation. Predicted to be part of protein-containing complex. Predicted to be active in cytosol. Is expressed in embryo. Orthologous to human METTL21EP (methyltransferase like 21E, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Mettl21e in Genome Data Viewer
Location:
1 C1.1; 1 23.63 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (44238651..44258260, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (44204070..44218931, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:44176158-44176267 Neighboring gene protein O-glucosyltransferase 2 Neighboring gene STARR-positive B cell enhancer mm9_chr1:44204561-44204862 Neighboring gene basic, immunoglobulin-like variable motif containing Neighboring gene excision repair cross-complementing rodent repair deficiency, complementation group 5 Neighboring gene predicted gene 15833 Neighboring gene STARR-seq mESC enhancer starr_00798 Neighboring gene STARR-seq mESC enhancer starr_00799 Neighboring gene STARR-seq mESC enhancer starr_00800 Neighboring gene FK506 binding protein 9 pseudogene Neighboring gene STARR-seq mESC enhancer starr_00801 Neighboring gene STARR-seq mESC enhancer starr_00802 Neighboring gene predicted gene 28893

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein-lysine methyltransferase METTL21E
Names
methyltransferase-like protein 21C pseudogene 1 homolog
methyltransferase-like protein 21E pseudogene homolog
methyltransferase-like protein LOC121952 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207281.3 → NP_997164.1  protein-lysine methyltransferase METTL21E

    See identical proteins and their annotated locations for NP_997164.1

    Status: PROVISIONAL

    Source sequence(s)
    AC110217
    Consensus CDS
    CCDS14931.1
    UniProtKB/Swiss-Prot
    Q8CDZ2
    Related
    ENSMUSP00000056481.4, ENSMUST00000054801.4
    Conserved Domains (1) summary
    cl17173
    Location:50 → 216
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    44238651..44258260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152247.1 → XP_036008140.1  protein-lysine methyltransferase METTL21E isoform X1

    Conserved Domains (1) summary
    cl17173
    Location:50 → 111
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CDZ2.1 GenPept UniProtKB/Swiss-Prot:Q8CDZ2

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