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dnajc27 DnaJ (Hsp40) homolog, subfamily C, member 27 [ Danio rerio (zebrafish) ]

Gene ID: 402784, updated on 2-Nov-2024

Summary

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Official Symbol
dnajc27provided by ZNC
Official Full Name
DnaJ (Hsp40) homolog, subfamily C, member 27provided by ZNC
Primary source
ZFIN:ZDB-GENE-081022-93
See related
Ensembl:ENSDARG00000070916 AllianceGenome:ZFIN:ZDB-GENE-081022-93
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rbj; zgc:194263; zgc:194279
Summary
Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in nucleus. Orthologous to human DNAJC27 (DnaJ heat shock protein family (Hsp40) member C27). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See dnajc27 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (33296620..33307886)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (33344122..33353288)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene proopiomelanocortin a Neighboring gene EFR3 homolog Ba (S. cerevisiae) Neighboring gene si:ch211-132f19.7 Neighboring gene xanthine dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RJLs: a new family of Ras-related GTP-binding proteins. Nepomuceno-Silva JL, et al. Gene, 2004 Mar 3. PMID 14980719
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dnaJ homolog subfamily C member 27
Names
rab and DnaJ domain-containing protein
NP_001007163.1
XP_005158785.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007162.2 → NP_001007163.1  dnaJ homolog subfamily C member 27

    See identical proteins and their annotated locations for NP_001007163.1

    Status: VALIDATED

    Source sequence(s)
    BC162873
    UniProtKB/Swiss-Prot
    Q6IMK3
    UniProtKB/TrEMBL
    B3DHR2
    Related
    ENSDARP00000127972.1, ENSDART00000154580.2
    Conserved Domains (3) summary
    cd06257
    Location:217 → 264
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    cd04119
    Location:17 → 184
    RJL; Rab GTPase family J-like (RabJ-like)
    smart00175
    Location:17 → 176
    RAB; Rab subfamily of small GTPases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    33296620..33307886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158728.5 → XP_005158785.1  dnaJ homolog subfamily C member 27 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B552, E7FCB8
    Related
    ENSDARP00000109834.1, ENSDART00000123114.3
    Conserved Domains (3) summary
    cd06257
    Location:217 → 264
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    cd04119
    Location:17 → 184
    RJL; Rab GTPase family J-like (RabJ-like)
    smart00175
    Location:17 → 176
    RAB; Rab subfamily of small GTPases

RNA

  1. XR_222434.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IMK3.1 GenPept UniProtKB/Swiss-Prot:Q6IMK3

Gene LinkOut

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