Gbeta76C G protein beta subunit 76C [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gbeta76Cprovided by FlyBase
Official Full Name: G protein beta subunit 76Cprovided by FlyBase
Primary source: FLYBASE:FBgn0004623
Locus tag: Dmel_CG8770
See related: AllianceGenome:FB:FBgn0004623
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG8770; DGqbeta; Dmel\CG8770; eGbeta; eye Gbeta; Galpha76C; gbe; Gbe; Gbeta; Gbeta76c; Gbetae; Gbeta[[e]]; Gbeta_76C; Gbeta{e}; Gqbeta; Gqbetae; G[q]; G[[beta76C]]; G[[beta]]; G[[beta]]e
Summary: Enables protein heterodimerization activity. Involved in activation of phospholipase C activity; regulation of signal transduction; and rhodopsin mediated signaling pathway. Located in cytoplasm and rhabdomere. Part of heterotrimeric G-protein complex. Is expressed in head and photoreceptor cell. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (19687637..19689992)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (19680737..19683092)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables phospholipase activator activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed
enables signaling receptor complex adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled opsin signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of opsin-mediated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of opsin-mediated signaling pathway	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of smoothened signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
involved_in phototransduction	IDA Inferred from Direct Assay more info	PubMed
involved_in phototransduction	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
part_of heterotrimeric G-protein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of heterotrimeric G-protein complex	IDA Inferred from Direct Assay more info	PubMed
located_in rhabdomere	IDA Inferred from Direct Assay more info	PubMed
located_in rhabdomere	TAS Traceable Author Statement more info	PubMed

Names: CG8770-PA; G protein beta-subunit 76C; G[[beta]] eye; Gbeta76C-PA; guanine nucleotide regulatory protein beta subunit

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