IQCF3 IQ motif containing F3 [Homo sapiens (human)] - Gene

Summary

Official Symbol: IQCF3provided by HGNC
Official Full Name: IQ motif containing F3provided by HGNC
Primary source: HGNC:HGNC:31816
See related: Ensembl:ENSG00000229972 AllianceGenome:HGNC:31816
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: Predicted to enable calmodulin binding activity. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward testis (RPKM 10.2) See more
Orthologs: mouse all
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Genomic context

Location:: 3p21.2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	3	NC_000003.12 (51826883..51830856)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	3	NC_060927.1 (51859902..51863875)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	3	NC_000003.11 (51860899..51864872)

Chromosome 3 - NC_000003.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Functional Annotations of Single-Nucleotide Polymorphism (SNP)-Based and Gene-Based Genome-Wide Association Studies Show Genes Affecting Keratitis Susceptibility.
Title: Functional Annotations of Single-Nucleotide Polymorphism (SNP)-Based and Gene-Based Genome-Wide Association Studies Show Genes Affecting Keratitis Susceptibility.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables calmodulin binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: IQ domain-containing protein F3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001085479.3 → NP_001078948.1 IQ domain-containing protein F3

See identical proteins and their annotated locations for NP_001078948.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.

Source sequence(s)

AA991812, BC171818

Consensus CDS

CCDS46837.1

UniProtKB/Swiss-Prot

B2RUV0, P0C7M6

Related

ENSP00000409373.2, ENST00000437810.7
NM_001207023.2 → NP_001193952.1 IQ domain-containing protein F3

See identical proteins and their annotated locations for NP_001193952.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.

Source sequence(s)

AA991812, BC146874

Consensus CDS

CCDS46837.1

UniProtKB/Swiss-Prot

B2RUV0, P0C7M6

Related

ENSP00000401767.1, ENST00000446775.5
NM_001393887.1 → NP_001380816.1 IQ domain-containing protein F3

Status: VALIDATED

Source sequence(s)

AC097636

Consensus CDS

CCDS46837.1

UniProtKB/Swiss-Prot

B2RUV0, P0C7M6

Related

ENSP00000402012.2, ENST00000440739.4