snrpc.S small nuclear ribonucleoprotein polypeptide C S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: snrpc.S
Official Full Name: small nuclear ribonucleoprotein polypeptide C S homeolog
Primary source: Xenbase:XB-GENE-866414
Locus tag: XELAEV_18014856mg
See related: EnsemblRapid:ENSXLAG00005001657 AllianceGenome:Xenbase:XB-GENE-866414
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: U1C; snrpc; snrp1c
Summary: Predicted to enable RNA binding activity and zinc ion binding activity. Predicted to act upstream of or within mRNA 5'-splice site recognition and spliceosomal snRNP assembly. Predicted to be located in nucleus. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease; mixed connective tissue disease; and systemic lupus erythematosus. Orthologous to human SNRPC (small nuclear ribonucleoprotein polypeptide C). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2S

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (58696412..58708087, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2S	NC_030727.1 (54663718..54675404, complement)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables U1 snRNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables pre-mRNA 5'-splice site binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA 5'-splice site recognition	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within spliceosomal snRNP assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U1 snRNP	IEA Inferred from Electronic Annotation more info
part_of U1 snRNP	ISS Inferred from Sequence or Structural Similarity more info
part_of U2-type prespliceosome	IEA Inferred from Electronic Annotation more info
part_of commitment complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U1 small nuclear ribonucleoprotein C

Names: U1 snRNP protein C; snRNP C protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090661.1 → NP_001084130.1 U1 small nuclear ribonucleoprotein C

See identical proteins and their annotated locations for NP_001084130.1

Status: PROVISIONAL

Source sequence(s)

BC084206

UniProtKB/Swiss-Prot

Q03369, Q5XH67

UniProtKB/TrEMBL

A0A974HVT9

Related

ENSXLAP00005004913.1, ENSXLAT00005005019.1

Conserved Domains (1) summary

pfam06220
Location:1 → 38

zf-U1; U1 zinc finger

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

58696412..58708087 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)