U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mtf2.S metal response element binding transcription factor 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399117, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
mtf2.S
Official Full Name
metal response element binding transcription factor 2 S homeolog
Primary source
Xenbase:XB-GENE-1014965
Locus tag
XELAEV_18025387mg
See related
EnsemblRapid:ENSXLAG00005009524 AllianceGenome:Xenbase:XB-GENE-1014965
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
mtf2; mtf2a; xpcl2
Summary
Predicted to enable several functions, including chromatin binding activity; metal ion binding activity; and methylated histone binding activity. Predicted to act upstream of or within chromatin organization and regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human MTF2 (metal response element binding transcription factor 2). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See mtf2.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (83807182..83831809, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (77484212..77512320, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 18 S homeolog Neighboring gene uncharacterized LOC121393328 Neighboring gene transmembrane p24 trafficking protein 5 S homeolog Neighboring gene divergent protein kinase domain 1A S homeolog Neighboring gene ribosomal protein L5 S homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Xenopus Polycomblike 2 (XPcl2) controls anterior to posterior patterning of the neural tissue. Kitaguchi T, et al. Dev Genes Evol, 2001 Jun. PMID 11466526
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC132044

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
metal response element binding transcription factor 2 S homeolog; metal-response element-binding transcription factor 2
Names
metal response element binding transcription factor 2 a
polycomblike 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    83807182..83831809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041561523.1 → XP_041417457.1  metal-response element-binding transcription factor 2 isoform X2

    UniProtKB/TrEMBL
    A0A974D0L2, Q2T9I8
    Related
    ENSXLAP00005027824.1, ENSXLAT00005028560.1
    Conserved Domains (4) summary
    cd15578
    Location:104 → 156
    PHD1_MTF2; PHD finger 1 found in metal-response element-binding transcription factor 2 (MTF2)
    cd15580
    Location:203 → 254
    PHD2_MTF2; PHD finger 2 found in metal-response element-binding transcription factor 2 (MTF2)
    pfam14061
    Location:544 → 591
    Mtf2_C; Polycomb-like MTF2 factor 2
    cd20450
    Location:45 → 97
    Tudor_MTF2; Tudor domain found in metal-response element-binding transcription factor 2 (MTF2) and similar proteins

  2. XM_018259514.2 → XP_018115003.1  metal-response element-binding transcription factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4E4, A0A974D0L2
    Related
    ENSXLAP00005027859.1, ENSXLAT00005028593.1

RNA

  1. XR_005960987.1 RNA Sequence

  2. XR_005960986.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001090316.1: Suppressed sequence

    Description
    NM_001090316.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.