U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lmpt Limpet [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39889, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Lmptprovided by FlyBase
Official Full Name
Limpetprovided by FlyBase
Primary source
FLYBASE:FBgn0261565
Locus tag
Dmel_CG42679
See related
AllianceGenome:FB:FBgn0261565
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE37250; CG11914; CG11915; CG11916; CG32171; CG33256; CG42679; CG9959; Dmel\CG42679; lmpt
Old locus tag
Dmel_CG11915; Dmel_CG32171; Dmel_CG33256
Summary
Predicted to enable zinc ion binding activity. Involved in defense response to fungus and negative regulation of canonical Wnt signaling pathway. Located in I band. Is expressed in several structures, including adult head; epithelium; gut section; larval muscle cell; and visceral muscle primordium. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Lmpt in Genome Data Viewer
Location:
73D3-73D6; 3-45 cM
Exon count:
21
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16865295..16922487)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16858395..16915587)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rhodopsin 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45898 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. Chi W, et al. G3 (Bethesda), 2014 Apr 16. PMID 24739647, Free PMC Article
  2. The function of Lmpt in Drosophila heart tissue. She M, et al. Biochem Biophys Res Commun, 2022 Jul 5. PMID 35500437
  3. Whole-genome expression profiles identify gene batteries in Drosophila. Stathopoulos A, et al. Dev Cell, 2002 Oct. PMID 12408796
  4. The evolution of transcriptional repressors in the Notch signaling pathway: a computational analysis. Maier D. Hereditas, 2019. PMID 30679936, Free PMC Article
  5. Lmpt regulates the function of Drosophila muscle by acting as a repressor of Wnt signaling. Zhang J, et al. Gene, 2023 Aug 5. PMID 37245676

See all (70) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Lmpt regulates the function of Drosophila muscle by acting as a repressor of Wnt signaling.
    Title: Lmpt regulates the function of Drosophila muscle by acting as a repressor of Wnt signaling.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in I band HDA PubMed 
located_in cytoplasm HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
limpet
Names
CG42679-PA
CG42679-PB
CG42679-PC
CG42679-PD
CG42679-PE
CG42679-PF
CG42679-PG
CG42679-PH
CG42679-PI
CG42679-PJ
CG42679-PK
CG42679-PL
CG42679-PM
CG42679-PO
CG42679-PP
Lmpt-PA
Lmpt-PB
Lmpt-PC
Lmpt-PD
Lmpt-PE
Lmpt-PF
Lmpt-PG
Lmpt-PH
Lmpt-PI
Lmpt-PJ
Lmpt-PK
Lmpt-PL
Lmpt-PM
Lmpt-PO
Lmpt-PP

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16865295..16922487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140673.5 → NP_648930.1  limpet, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648930.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95PU4, Q9VVB5
    Related
    FBpp0291921
    Conserved Domains (7) summary
    cd09414
    Location:193 → 250
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:256 → 311
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:314 → 372
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:379 → 432
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:440 → 491
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:499 → 554
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:100 → 183
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  2. NM_001259879.2 → NP_001246808.1  limpet, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246808.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95PU4, Q9VVB5
    Conserved Domains (7) summary
    cd09414
    Location:193 → 250
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:256 → 311
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:314 → 372
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:379 → 432
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:440 → 491
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:499 → 554
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:100 → 183
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  3. NM_206388.3 → NP_996110.1  limpet, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996110.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95PU4, Q9VVB5
    Conserved Domains (7) summary
    cd09414
    Location:193 → 250
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:256 → 311
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:314 → 372
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:379 → 432
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:440 → 491
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:499 → 554
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:100 → 183
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  4. NM_001275047.1 → NP_001261976.2  limpet, isoform P [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PFX9
    Conserved Domains (7) summary
    cd09414
    Location:193 → 250
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:256 → 311
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:314 → 372
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:379 → 432
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:440 → 491
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:499 → 554
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:100 → 183
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  5. NM_206387.3 → NP_996109.1  limpet, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996109.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IQQ3
    Conserved Domains (7) summary
    cd09414
    Location:192 → 249
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:255 → 310
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:313 → 371
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:378 → 431
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:439 → 490
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:498 → 553
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:99 → 182
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  6. NM_170635.3 → NP_730212.1  limpet, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730212.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IQQ3
    Related
    FBpp0291922
    Conserved Domains (7) summary
    cd09414
    Location:192 → 249
    LIM1_LIMPETin; The first LIM domain of protein LIMPETin
    cd09417
    Location:255 → 310
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:313 → 371
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:378 → 431
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:439 → 490
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:498 → 553
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cd09830
    Location:99 → 182
    PET_LIMPETin_LIM-9; The PET domain of protein LIMPETin and LIM-9

  7. NM_001202193.2 → NP_001189122.1  limpet, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189122.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRX0
    Conserved Domains (7) summary
    cd09417
    Location:694 → 741
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:744 → 802
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:809 → 862
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:870 → 921
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:929 → 984
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    pfam15346
    Location:110 → 255
    ARGLU; Arginine and glutamate-rich 1
    cl21478
    Location:100 → 181
    ATP-synt_B; ATP synthase B/B' CF(0)

  8. NM_206391.3 → NP_996113.2  limpet, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996113.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KUQ6
    Conserved Domains (3) summary
    pfam15346
    Location:110 → 255
    ARGLU; Arginine and glutamate-rich 1
    cd16269
    Location:170 → 181
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:103 → 201
    GBP_C; Guanylate-binding protein, C-terminal domain

  9. NM_140674.4 → NP_648931.1  limpet, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648931.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95SL1, Q9VVB6
    Conserved Domains (1) summary
    cl20817
    Location:124 → 199
    GBP_C; Guanylate-binding protein, C-terminal domain

  10. NM_206389.3 → NP_996111.1  limpet, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996111.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KUQ5, Q8MYZ5
    Conserved Domains (5) summary
    cd09421
    Location:41 → 99
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:106 → 159
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:167 → 218
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:226 → 281
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cl02475
    Location:1 → 38
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  11. NM_168694.3 → NP_730213.1  limpet, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730213.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MYZ5, Q9VVB7
    Related
    FBpp0291923
    Conserved Domains (5) summary
    cd09417
    Location:36 → 91
    LIM2_LIMPETin_like; The second LIM domain of protein LIMPETin and related proteins
    cd09421
    Location:94 → 152
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:159 → 212
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:220 → 271
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:279 → 334
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin

  12. NM_001316485.1 → NP_001303414.1  limpet, isoform O [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KUQ5, Q8MYZ5
    Conserved Domains (5) summary
    cd09421
    Location:41 → 99
    LIM3_LIMPETin; The third LIM domain of protein LIMPETin
    cd09425
    Location:106 → 159
    LIM4_LIMPETin; The fourth LIM domain of protein LIMPETin
    cd09430
    Location:167 → 218
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:226 → 281
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cl02475
    Location:1 → 38
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  13. NM_206390.2 → NP_996112.1  limpet, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996112.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVB8
    Conserved Domains (3) summary
    cd09430
    Location:126 → 177
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:185 → 240
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cl02475
    Location:73 → 118
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  14. NM_001169985.1 → NP_001163456.1  limpet, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163456.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVB8
    Conserved Domains (3) summary
    cd09430
    Location:126 → 177
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:185 → 240
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cl02475
    Location:73 → 118
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  15. NM_140676.4 → NP_648933.3  limpet, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648933.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVB8
    Related
    FBpp0291916
    Conserved Domains (3) summary
    cd09430
    Location:126 → 177
    LIM5_LIMPETin; The fifth LIM domain of protein LIMPETin
    cd09432
    Location:185 → 240
    LIM6_LIMPETin; The sixth LIM domain of protein LIMPETin
    cl02475
    Location:73 → 118
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9MRX0 M9MRX0
M9PFX9 M9PFX9
Q7KUQ5 Q7KUQ5
Q7KUQ6 Q7KUQ6
Q8IQQ3 Q8IQQ3
Q8MYZ5 Q8MYZ5
Q9VVB5 Q9VVB5
Q9VVB6 Q9VVB6
Q9VVB7 Q9VVB7
Q9VVB8 Q9VVB8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools