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eed.S embryonic ectoderm development S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398420, updated on 4-Nov-2024

Summary

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Official Symbol
eed.S
Official Full Name
embryonic ectoderm development S homeolog
Primary source
Xenbase:XB-GENE-491484
Locus tag
XELAEV_18016352mg
See related
EnsemblRapid:ENSXLAG00005000193 AllianceGenome:Xenbase:XB-GENE-491484
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
eed; Xeed; eed-a; eed-b; wait1; Xeed-B; psXEED
Summary
Predicted to enable nucleosome binding activity. Predicted to act upstream of or within chromatin organization and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex. Orthologous to human EED (embryonic ectoderm development). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See eed.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (160249215..160271662, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (150914793..150937374, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene NADP-dependent malic enzyme, mitochondrial-like Neighboring gene nik-related protein kinase Neighboring gene chloride channel, nucleotide-sensitive, 1A S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Xenopus EED pseudogene, a Polycomb group gene. Cho JK, et al. DNA Seq, 2002 Aug. PMID 12487026
  2. The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos. Satijn DP, et al. Mol Cell Biol, 2001 Feb. PMID 11158321, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC82196

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables nucleosome binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ESC/E(Z) complex IEA
Inferred from Electronic Annotation
more info
  
part_of ESC/E(Z) complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
polycomb protein eed-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088885.1 → NP_001082354.1  polycomb protein eed-B

    See identical proteins and their annotated locations for NP_001082354.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077425
    UniProtKB/Swiss-Prot
    Q6AZS2, Q8AV63, Q8AV64, Q90YL5
    Related
    ENSXLAP00005000539.1, ENSXLAT00005000566.1
    Conserved Domains (3) summary
    COG2319
    Location:66 → 425
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:81 → 125
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:135 → 423
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    160249215..160271662 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AZS2.2 GenPept UniProtKB/Swiss-Prot:Q6AZS2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials