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stmn1.L stathmin 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397962, updated on 4-Nov-2024

Summary

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Official Symbol
stmn1.L
Official Full Name
stathmin 1 L homeolog
Primary source
Xenbase:XB-GENE-6252151
Locus tag
XELAEV_18012146mg
See related
EnsemblRapid:ENSXLAG00005024399 AllianceGenome:Xenbase:XB-GENE-6252151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
op18; xo35; stmn1b; stmn1-a; stmn1-b; stathmin
Summary
Enables tubulin binding activity. Acts upstream of or within with a negative effect on microtubule nucleation. Predicted to be located in cytoplasm; microtubule; and neuron projection. Orthologous to human STMN1 (stathmin 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See stmn1.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (62590083..62601631)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (59890933..59902447)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene pancreatic secretory granule membrane major glycoprotein GP2-like gene 3 L homeolog Neighboring gene platelet-activating factor acetylhydrolase 2 L homeolog Neighboring gene aurora kinase A and ninein-interacting protein Neighboring gene abhydrolase domain containing 10 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle. Houghtaling BR, et al. Proc Natl Acad Sci U S A, 2009 Sep 8. PMID 19706424, Free PMC Article
  2. The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy. Thawani A, et al. Elife, 2020 Jun 15. PMID 32538784, Free PMC Article
  3. Stathmin gene family: phylogenetic conservation and developmental regulation in Xenopus. Maucuer A, et al. J Biol Chem, 1993 Aug 5. PMID 8344928
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.
    Title: Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables tubulin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule depolymerization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within_negative_effect microtubule nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within neuron projection development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of microtubule polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
stathmin-1-A
Names
oncoprotein 18
stathmin 1 b
stathmin 1b
stathmin clone XO35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088158.1 → NP_001081627.1  stathmin-1-A

    See identical proteins and their annotated locations for NP_001081627.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073451
    UniProtKB/Swiss-Prot
    Q09006, Q6GNQ3
    UniProtKB/TrEMBL
    A0A974HXZ8
    Related
    ENSXLAP00005072374.1, ENSXLAT00005073923.1
    Conserved Domains (1) summary
    pfam00836
    Location:9 → 138
    Stathmin; Stathmin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    62590083..62601631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018244871.2 → XP_018100360.1  stathmin-1-A isoform X1

    UniProtKB/Swiss-Prot
    Q09006, Q6GNQ3
    UniProtKB/TrEMBL
    A0A974HXZ8

  2. XM_018244872.1 → XP_018100361.1  stathmin-1-A isoform X1

    UniProtKB/Swiss-Prot
    Q09006, Q6GNQ3
    UniProtKB/TrEMBL
    A0A974HXZ8
    Related
    ENSXLAP00005072332.1, ENSXLAT00005073881.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09006.1 GenPept UniProtKB/Swiss-Prot:Q09006

Gene LinkOut

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Molecular Biology Databases
Research Materials