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ITGAV integrin subunit alpha V [ Gallus gallus (chicken) ]

Gene ID: 396420, updated on 10-Oct-2024

Summary

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Symbol
ITGAVprovided by CGNC
Full Name
integrin subunit alpha Vprovided by CGNC
Primary source
CGNC:1912
See related
Ensembl:ENSGALG00010013386
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ITGAV in Genome Data Viewer
Location:
chromosome: 7
Exon count:
31
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (1402712..1451372, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (1341846..1390500, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene microRNA 1812 Neighboring gene family with sequence similarity 171 member B Neighboring gene uncharacterized LOC112532756 Neighboring gene microRNA 1559 Neighboring gene uncharacterized LOC101747532 Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene uncharacterized LOC121111308

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chick integrin alpha V subunit molecular analysis reveals high conservation of structural domains and association with multiple beta subunits in embryo fibroblasts. Bossy B, et al. Biochemistry, 1990 Nov 6. PMID 1703004, Free PMC Article
  2. On the mechanism of thrombin-induced angiogenesis: involvement of alphavbeta3-integrin. Tsopanoglou NE, et al. Am J Physiol Cell Physiol, 2002 Nov. PMID 12372811
  3. Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta. Mikelis C, et al. FASEB J, 2009 May. PMID 19141530
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-V
Names
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
vitronectin receptor alpha subunit
vitronectin receptor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205439.2 → NP_990770.2  integrin alpha-V precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000235
    UniProtKB/Swiss-Prot
    P26008
    UniProtKB/TrEMBL
    A0A8V0YJP7
    Related
    ENSGALP00010019036.1, ENSGALT00010032246.1
    Conserved Domains (2) summary
    smart00191
    Location:354 → 409
    Int_alpha; Integrin alpha (beta-propellor repeats)
    sd00039
    Location:176 → 230
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1402712..1451372 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046943520.1 → XP_046799476.1  integrin alpha-V isoform X1

    Related
    ENSGALP00010019048.1, ENSGALT00010032259.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1341846..1390500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921187.1 → XP_046777143.1  integrin alpha-V isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26008.1 GenPept UniProtKB/Swiss-Prot:P26008

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials